2,5-Dioxopyrrolidin-1-yl 3-iodo-4-methoxybenzoate CAS 727659-89-4
| CAS No. | 727659-89-4 |
| Molecular Formula | C12H10INO5 |
| Molecular Weight | 375.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 2,5-Dioxopyrrolidin-1-yl 3-iodo-4-methoxybenzoate (CAS 727659-89-4), a certified reference material (molecular formula C12H10INO5, MW 375.12 g/mol) for analytical method development and quality control.
The molecular framework of 2,5-Dioxopyrrolidin-1-yl 3-iodo-4-methoxybenzoate (C12H10INO5) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H10INO5 |
| Molecular Weight | 375.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Dioxopyrrolidin Standards
- 7-((1-Butyl-2,5-dioxopyrrolidin-3-yl)sulfonyl)heptyl acetate (CAS 62163-96-6)
- 2-(2,5-Dioxopyrrolidin-1-yl)-N-(4-(4-propoxyphenyl)thiazol-2-yl)acetamide (CAS 392324-75-3)
- (E)-2-(2,5-Dioxopyrrolidin-1-yl)-N-((1-(3-(furan-2-yl)acryloyl)piperidin-4-yl)methyl)acetamide (CAS 1235679-04-5)
- 2-(2-(2-(3-((2,5-Dioxopyrrolidin-1-yl)oxy)-3-oxopropoxy)ethoxy)ethoxy)ethyl acrylate (CAS 1042435-35-7)
- bis(2,5-dioxopyrrolidin-1-yl) 2,2'-(ethane-1,2-diylbis(oxy))diacetate (CAS 441052-81-9)
- (S)-4-(2,5-Dioxopyrrolidin-1-yl) 1-methyl 2-(((benzyloxy)carbonyl)amino)succinate (CAS 54743-84-9)
- (S)-2,5-Dioxopyrrolidin-1-yl 2-(((benzyloxy)carbonyl)amino)-4-(methylthio)butanoate (CAS 3392-01-6)
- 4-(2,5-Dioxopyrrolidin-1-yl)-N-nonylbenzenesulfonamide (CAS 61633-11-2)
Recommended Standards
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- 2,4-Dibromo-6-[(1E)-(cycloheptylimino)methyl]phenol (CAS 477847-01-1)
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- 4-Chloro-2,5-difluorobenzoic acid ethyl ester (CAS 879093-03-5)
- D-[Ser]11-Semaglutide (CAS CATO-CPTD788629)
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