1-(5-Chloro-2-methyl-4-nitrophenyl)-1H-tetrazole CAS 727675-31-2
| CAS No. | 727675-31-2 |
| Molecular Formula | C8H6ClN5O2 |
| Molecular Weight | 239.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(5-Chloro-2-methyl-4-nitrophenyl)-1H-tetrazole (CAS 727675-31-2) is a high-purity analytical reference standard with the molecular formula C8H6ClN5O2 and a molecular weight of 239.62 g/mol.
Based on its molecular formula C8H6ClN5O2, 1-(5-Chloro-2-methyl-4-nitrophenyl)-1H-tetrazole contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 239.62 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 1-(5-Chloro-2-methyl-4-nitrophenyl)-1H-tetrazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6ClN5O2 |
| Molecular Weight | 239.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Chloro Standards
- 1-(6-Chloro-4-nitro-1H-indazol-1-yl)ethanone (CAS 1010102-85-8)
- 1-(3-Chloro-4-methoxyphenyl)-2,2,2-trifluoroethan-1-amine (CAS 1039923-43-7)
- 5-(2-Chloro-5-nitrophenyl)-3-methyl-1,2,4-oxadiazole (CAS 1119395-85-5)
- (S)-1-(3-chloro-4-methoxyphenyl)-2,2,2-trifluoroethan-1-amine (CAS 1212828-23-3)
- (R)-1-(3-chloro-4-methoxyphenyl)-2,2,2-trifluoroethan-1-amine (CAS 1213932-14-9)
- (R)-1-(5-Chloro-2-methoxyphenyl)-2,2,2-trifluoroethan-1-amine (CAS 1213956-30-9)
- (S)-1-(3-chloro-5-methoxyphenyl)-2,2,2-trifluoroethan-1-amine (CAS 1272740-44-9)
- (R)-1-(3-chloro-5-methoxyphenyl)-2,2,2-trifluoroethan-1-amine (CAS 1272748-83-0)
Recommended Standards
- 1-(5-Chloro-2-methoxyphenyl)-2,2,2-trifluoroethan-1-amine (CAS 886371-36-4)
- 2-(3-Chlorophenoxy)-3,3,3-trifluoropropan-1-amine (CAS 886763-82-2)
- 1-(3-Chloro-5-nitro-1H-indazol-1-yl)ethan-1-one (CAS 68159-07-9)
- 2-(chloromethyl)-5-(2-nitrophenyl)-1,3,4-oxadiazole (CAS 63002-55-1)
- 1-Cyclopropyl-3-(2-methylpropyl)piperazine (CAS 1248907-63-2)
- (2-Cyanopyrimidin-4-yl)boronic acid (CAS 1309981-55-2)
- 6-Methoxy-N-(2-(3-methylisoxazol-5-yl)ethyl)-1H-indole-2-carboxamide (CAS 1421443-68-6)
- 2-(1-Benzylpiperidin-3-yl)ethanamine (CAS 1083181-70-7)
- 4-Bromo-1-(1-methylcyclopropyl)-1H-pyrazole (CAS 1628214-21-0)
- 2-(Bromomethyl)phenyl Acetate (CAS 704-65-4)
- 2-Amino-5-methyl-5-phenyloxazol-4(5H)-one (CAS 51038-39-2)
- 4-(3-Methoxypyridin-2-yl)tetrahydro-2h-pyran-4-carboxylic acid (CAS 1439899-49-6)
- 1-[(4-iodophenyl)carbamoyl]cyclopropane-1-carboxylic acid (CAS 1247901-32-1)
- Tirzepatide Impurity 22 X TFA Salt (CAS CATO-C4X-324022)
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