2,2-Difluoro-5-(hydroxymethyl)-1,3-benzodioxole CAS 72768-97-9
| CAS No. | 72768-97-9 |
| Molecular Formula | C8H6F2O3 |
| Molecular Weight | 188.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2,2-Difluoro-5-(hydroxymethyl)-1,3-benzodioxole (CAS 72768-97-9), molecular formula C8H6F2O3 and molecular weight 188.13 g/mol, is a CATO reference standard with documented purity and traceability.
2,2-Difluoro-5-(hydroxymethyl)-1,3-benzodioxole (C8H6F2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 2,2-Difluoro-5-(hydroxymethyl)-1,3-benzodioxole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6F2O3 |
| Molecular Weight | 188.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 2-(2,5-Difluoro-4-hydroxyphenyl)acetic acid (CAS 1042703-29-6)
- 2-(3,5-Difluoro-4-hydroxyphenyl)acetic acid (CAS 1042703-32-1)
- 2,5-Difluoro-4-methoxybenzoic acid (CAS 1060739-01-6)
- 2,4-DIFLUORO-3-METHYL-5-NITROBENZENAMINE (CAS 112822-77-2)
- (2,4-Difluoro-5-nitrophenyl)methanamine (CAS 1158049-24-1)
- 3,5-Difluoro-4-(hydroxymethyl)benzoic acid (CAS 1211596-29-0)
- Methyl 3,6-difluoro-2-hydroxybenzoate (CAS 1214324-50-1)
- 2,6-Difluoro-3-hydroxy-benzoic acid methyl ester (CAS 1214332-41-8)
Recommended Standards
- 2,2-Difluoro-2-phenoxyacetic acid (CAS 24210-45-5)
- 2,3-Difluoro-4-methoxybenzoic Acid (CAS 329014-60-0)
- 2-(Difluoromethoxy)isonicotinamide (CAS 2167739-11-7)
- 2,3-Difluoro-6-methoxybenzoic Acid (CAS 773873-26-0)
- 1-(4-Ethylphenyl)piperidine-4-carboxylic acid (CAS 1241894-78-9)
- CAS 89947-80-8 (CAS 89947-80-8)
- 1-(6-Methylpyrimidin-4-yl)piperidin-3-ol (CAS 1249221-92-8)
- DCG04 (CAS 314263-42-8)
- 2-Fluoro-6-(methylthio)benzonitrile (CAS 119584-71-3)
- 2,4-Difluoro-N-(2-methoxypyrimidin-5-yl)benzenesulfonamide (CAS 1421441-53-3)
- 2-(4-Chlorophenyl)-6-methoxypyridine (CAS 486455-36-1)
- 4-(Aminomethyl)-2-cyano-6-hydroxybenzene-1-sulfonyl chloride (CAS 1805096-04-1)
- 3-(((2-(1-Methyl-1h-pyrazol-4-yl)ethyl)amino)methyl)benzonitrile (CAS 1240872-57-4)
- Tau Peptide (306-317) trifluoroacetate salt (CAS 1003007-59-7)
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