4-amino-1-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)-2-oxolanyl]-2-pyrimidinone 4-azanyl-1-[(2R,3R,5S)-5-(hydroxymethyl)-3-oxidanyl-oxolan-2-yl]pyrimidin-2-one 728-86-9 A837654 CAS 728-86-9

Purity 97%+In StockPharmaceutical Standards
CAS No.728-86-9
Molecular FormulaC14H9F3O
Molecular Weight250.22 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-amino-1-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)-2-oxolanyl]-2-pyrimidinone
4-azanyl-1-[(2R,3R,5S)-5-(hydroxymethyl)-3-oxidanyl-oxolan-2-yl]pyrimidin-2-one
728-86-9
A837654 CAS 728-86-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-amino-1-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)-2-oxolanyl]-2-pyrimidinone 4-azanyl-1-[(2R,3R,5S)-5-(hydroxymethyl)-3-oxidanyl-oxolan-2-yl]pyrimidin-2-one 728-86-9 A837654.

CATO supplies 4-amino-1-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)-2-oxolanyl]-2-pyrimidinone 4-azanyl-1-[(2R,3R,5S)-5-(hydroxymethyl)-3-oxidanyl-oxolan-2-yl]pyrimidin-2-one 728-86-9 A837654 (CAS 728-86-9), a certified reference material (molecular formula C14H9F3O, MW 250.22 g/mol) for analytical method development and quality control.

Structurally, 4-amino-1-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)-2-oxolanyl]-2-pyrimidinone 4-azanyl-1-[(2R,3R,5S)-5-(hydroxymethyl)-3-oxidanyl-oxolan-2-yl]pyrimidin-2-one 728-86-9 A837654 (C14H9F3O) contains a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 250.22 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), 4-amino-1-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)-2-oxolanyl]-2-pyrimidinone 4-azanyl-1-[(2R,3R,5S)-5-(hydroxymethyl)-3-oxidanyl-oxolan-2-yl]pyrimidin-2-one 728-86-9 A837654 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H9F3O
Molecular Weight250.22 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentF-containing

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