Estropipate CAS 7280-37-7
| CAS No. | 7280-37-7 |
| Molecular Formula | C18H22O5S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Estropipate.
Estropipate (CAS 7280-37-7), molecular formula C18H22O5SC4H10N2 and molecular weight 436.57 g/mol, is a CATO reference standard with documented purity and traceability.
Estropipate (C18H22O5SC4H10N2) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Estropipate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H22O5S C4H10N2 |
| Molecular Weight | 436.57 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Recommended Standards
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- Mianserin Impurity 13 (CAS 91247-76-6)
- 2-(1,1-Dioxidothiomorpholino)-3-(1H-indol-3-yl)-N-(thiophen-2-ylmethyl)propanamide (CAS 478040-66-3)
- 67385-09-5 N-(tert-Butoxycarbonyl)-2-aminoethanethiol Carbamic acid, (2-mercaptoethyl)-, 1,1-dimethylethyl ester N-Boc-aet (CAS 67385-09-5)
- 1-Acetyl-5-bromo-4-chloro-pseudoindoxyl (CAS 116270-39-4)
- 4-(1-((1-Phenyl-1H-1,2,4-triazol-3-yl)oxy)ethyl)pyrimidin-2-amine (CAS 320416-48-6)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (3-acetylfuran-2-yl)boronate (CAS 2223029-74-9)
- rel-methyl (2R,4R)-4-(((benzyloxy)carbonyl)amino)pyrrolidine-2-carboxylate hydrochloride (CAS 1217654-88-0)
- Semaglutide Impurity 3 (CAS CATO-C4X-22263)
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