3-Amino-6-(propan-2-yl)-N-[4-(trifluoromethoxy)phenyl]-5H,6H,7H,8H-thieno[2,3-b]1,6-naphthyridine-2-carboxamide CAS 728025-83-0
| CAS No. | 728025-83-0 |
| Molecular Formula | C21H21F3N4O2S |
| Molecular Weight | 450.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 450.48 g/mol gives 3-Amino-6-(propan-2-yl)-N-[4-(trifluoromethoxy)phenyl]-5H,6H,7H,8H-thieno[2,3-b]1,6-naphthyridine-2-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-Amino-6-(propan-2-yl)-N-[4-(trifluoromethoxy)phenyl]-5H,6H,7H,8H-thieno[2,3-b]1,6-naphthyridine-2-carboxamide (CAS 728025-83-0), molecular formula C21H21F3N4O2S and molecular weight 450.48 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C21H21F3N4O2S, 3-Amino-6-(propan-2-yl)-N-[4-(trifluoromethoxy)phenyl]-5H,6H,7H,8H-thieno[2,3-b]1,6-naphthyridine-2-carboxamide contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 450.48 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Amino-6-(propan-2-yl)-N-[4-(trifluoromethoxy)phenyl]-5H,6H,7H,8H-thieno[2,3-b]1,6-naphthyridine-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H21F3N4O2S |
| Molecular Weight | 450.48 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 2-(3,4-Bis(benzyloxy)phenyl)-3-hydroxy-4H-chromen-4-one (CAS 307521-00-2)
- endo-BCN-PEG2-C2-NHS ester (CAS 2243565-12-8)
- [5-(Benzenesulfonyl)-1-methyl-3-phenyl-1H-pyrazol-4-yl]methyl 4-fluorobenzoate (CAS 318289-30-4)
- Fmoc-Leu-OSu (CAS 76542-83-1)
- N-(4-(4,5-dichloro-1H-imidazol-1-yl)phenyl)naphthalene-2-sulfonamide (CAS 1023356-72-0)
- 3-(3,5-Dimethyl-4-nitro-1h-pyrazol-1-yl)-2-methylpropanoic acid (CAS 1005640-74-3)
- 3-Bromo-5-chloro-2-(2-methylpropoxy)pyridine (CAS 1289133-42-1)
- (1-(2-(Methylthio)benzyl)piperidin-4-yl)methanamine (CAS 1447965-80-1)
- N-Isopropylglycinamide (CAS 67863-05-2)
- Methyl 4-methyl-6-(piperidin-1-yl)nicotinate (CAS 1355219-66-7)
- 4-Octyloxybenzohydrazide (CAS 55510-49-1)
- 2-(4-Fluoro-2,6-dimethylbenzylidene)malononitrile (CAS 771564-67-1)
- 2-(4-Nitrophenyl)ethane-1-sulfonamide (CAS 90007-78-6)
- Peptide YY (canine, mouse, porcine, rat) trifluoroacetate salt (CAS 81858-94-8)
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