Torasemide EP Impurity E CAS 72810-57-2
| CAS No. | 72810-57-2 |
| Molecular Formula | C15H17N3O4S |
| Molecular Weight | 335.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Torasemide EP Impurity E meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Torasemide EP Impurity E (CAS 72810-57-2, C15H17N3O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Torasemide EP Impurity E is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 335.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C15H17N3O4S |
| Molecular Weight | 335.38 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Torasemide Standards
- Torasemide EP Impurity C (CAS 58155-35-4)
- Torasemide Impurity 6 (CAS 106944-63-2)
- Torasemide Impurity 7 (CAS 106944-62-1)
- Torasemide Impurity 22 (CAS CATO-C4X-183622)
- Torasemide impurity 41 (CAS CATO-C4X-183641)
- Torasemide EP Impurity D (CAS 160972-33-8)
- Torasemide Impurity 44 (CAS CATO-C4X-183644)
- Torasemide impurity 40 (CAS CATO-C4X-183640)
Recommended Standards
- Ilaprazole Impurity 93 (CAS CATO-C4X-113093)
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- Glutathione-monoethyl ester (reduced) (CAS 92614-59-0)
- Dimemorfan Phosphate Impurity 12 (CAS CATO-C4X-335812)
- Esomeprazole Impurity 38 (CAS 143016-68-6)
- Mianserin Impurity 102 HCl (CAS 131962-87-3)
- 3-amino-2-methoxybenzamide (CAS 1261498-13-8)
- 4-(((Tert-butoxycarbonyl)amino)methyl)piperidine-4-carboxylic acid (CAS 1890152-67-6)
- (R)-2-Amino-2-(3-bromo-4-methoxyphenyl)ethan-1-ol (CAS 1213677-18-9)
- 2,2,6,6-Tetramethyl-3,5-heptanedionato potassium, min. 95% [K(TMHD)] (CAS 22441-14-1)
- (R)-2-Ethylpiperazine, 97% (CAS 393781-72-1)
- 5-Hydroxy-6-methylquinolin-2(1H)-one (CAS 141695-96-7)
- D-Ile27-Tirzepatide (CAS CATO-CPTD788907)
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