5α-PREGNAN-3β, 11β, 20β, 21-TETROL CAS 7285-27-0
| CAS No. | 7285-27-0 |
| Molecular Formula | C21H36O4 |
| Molecular Weight | 352.51 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5α-PREGNAN-3β, 11β, 20β, 21-TETROL (C21H36O4) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
5α-PREGNAN-3β, 11β, 20β, 21-TETROL (CAS 7285-27-0), molecular formula C21H36O4 and molecular weight 352.51 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H36O4 |
| Molecular Weight | 352.51 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
Related PREGNAN Standards
- 5β-PREGNAN-3α, 11β, 17, 20α-TETROL (CAS 1242-48-4)
- 5β-PREGNAN-3α, 11β, 17, 20β-TETROL (CAS 2434-06-2)
- 5α-PREGNAN-3β, 11β, 21-TRIOL-20-ONE (CAS 516-16-5)
- 5α-PREGNAN-3β, 17, 21-TRIOL-20-ONE (CAS 516-47-2)
- 5α-PREGNAN-17, 21-DIOL-3, 20-DIONE (CAS 312-99-2)
- 5α-PREGNAN-3β, 21-DIOL-11, 20-DIONE (CAS 566-02-9)
- 5β-PREGNAN-17, 21-DIOL-3, 20-DIONE (CAS 566-42-7)
- 5β-Pregnan-21-ol-3,11,20-trione (CAS 10417-86-4)
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