2-Chloro-4-(3-methylpiperidine-1-carboxamido)benzenesulfonyl chloride CAS 728864-75-3
| CAS No. | 728864-75-3 |
| Molecular Formula | C13H16Cl2N2O3S |
| Molecular Weight | 351.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Chloro-4-(3-methylpiperidine-1-carboxamido)benzenesulfonyl chloride (C13H16Cl2N2O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-Chloro-4-(3-methylpiperidine-1-carboxamido)benzenesulfonyl chloride (CAS 728864-75-3), molecular formula C13H16Cl2N2O3S and molecular weight 351.25 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-4-(3-methylpiperidine-1-carboxamido)benzenesulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H16Cl2N2O3S |
| Molecular Weight | 351.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 3-Chloro-N-(2-chloro-5-(pyrrolidin-1-ylsulfonyl)phenyl)propanamide (CAS 1087784-08-4)
- 2-Chloro-4-(4-methylpiperidine-1-carboxamido)benzene-1-sulfonyl chloride (CAS 728864-76-4)
- 2-Chloro-N-[2-chloro-5-(piperidine-1-sulfonyl)phenyl]acetamide (CAS 379255-33-1)
- 6-Chloro-2-(4-chlorophenyl)-4-phenylquinazoline (CAS 49797-11-7)
- 3-Chloro-5-(4-chlorophenyl)-4-(2,6-difluorophenyl)-6-methylpyridazine (CAS 871513-21-2)
- 1-(3-Chloro-4-fluorophenyl)-3-(4-chlorophenyl)-1h-pyrazole-5-carboxylic acid (CAS 618102-45-7)
- 5-Chloro-4-(4-chlorophenoxy)-2-(4-fluorophenyl)-2,3-dihydropyridazin-3-one (CAS 551921-40-5)
- 3-(4-Chloro-3-methyl-phenyl)-propan-1-ol (CAS 1093173-25-1)
Recommended Standards
- 2,2-Dichloro-N-(4-(6-methylbenzo[d]thiazol-2-yl)phenyl)acetamide (CAS 349616-50-8)
- 2-(2,4-Dichlorophenyl)-5,6,7,8-tetrahydrobenzo[d]imidazo[2,1-b]thiazole-3-carbaldehyde (CAS 478029-48-0)
- 2-((2,4-Dichlorophenyl)thio)-1-(2-methylimidazo[1,2-a]pyridin-3-yl)ethan-1-one (CAS 861209-08-7)
- 3-(2,4-Dichlorophenyl)-2-methoxy-5-(phenylthio)furan (CAS 941270-41-3)
- (2,4-Dichlorophenyl)(4-methylpyridin-3-yl)methanone (CAS 1187169-05-6)
- Obeticholic Acid Impurity 52 (CAS 60354-42-9)
- 6-(Vinyloxy)quinoline (CAS 59195-18-5)
- 2,4-Dimethyl-3-fluoro-bromobenzene (CAS 26584-26-9)
- 4-(1,3-Dioxolan-2-yl)-2-fluorobenzophenone (CAS 898760-46-8)
- Sodium 7-methoxynaphthalene-2-sulfonate (CAS 60949-02-2)
- N-[(1R,2R)-2-[(11bR)-3,5-Dihydro-4H-dinaphth[2,1-c:1',2'-e]azepin-4-yl]-1,2-diphenylethyl]-4-methylbenzenesulfonamide (CAS 1034835-91-0)
- (E)-N'-carbamothioyl-N,N-dimethylformimidamide (CAS 83490-20-4)
- 1,2,3,4-tetrahydronaphthalene-1-carboximidamide hydrochloride (CAS 1375996-89-6)
- Semaglutide Impurity 13 (CAS CATO-C4X-222613)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com