{[2-(trifluoromethyl)phenyl]carbamoyl}methyl (2e)-3-(3-methoxyphenyl)prop-2-enoate CAS 728927-30-8
| CAS No. | 728927-30-8 |
| Molecular Formula | C19H16F3NO4 |
| Molecular Weight | 379.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies {[2-(trifluoromethyl)phenyl]carbamoyl}methyl (2e)-3-(3-methoxyphenyl)prop-2-enoate (CAS 728927-30-8), a certified reference material (molecular formula C19H16F3NO4, MW 379.33 g/mol) for analytical method development and quality control.
The molecular framework of {[2-(trifluoromethyl)phenyl]carbamoyl}methyl (2e)-3-(3-methoxyphenyl)prop-2-enoate (C19H16F3NO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H16F3NO4 |
| Molecular Weight | 379.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 2-{[(2,6-dichlorophenyl)methyl]sulfanyl}-4-[(E)-2-(thiophen-2-yl)ethenyl]pyrimidine (CAS 339278-42-1)
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- 3-Bromobenzenesulfonohydrazide (CAS 89862-26-0)
- 4-(Tert-butyl)-N,N-diethylbenzamide (CAS 20916-70-5)
- Ethyl 6-fluoro-1H-benzo[d]imidazole-4-carboxylate (CAS 1805680-72-1)
- 2-(2-Butoxy-3,5-difluorophenyl)ethan-1-ol (CAS 1443344-04-4)
- 2-Amino-9-benzyl-1H-purin-6(9H)-one (CAS 14937-72-5)
- 2-Chloro-6-(difluoromethyl)-3-hydroxyisonicotinic acid (CAS 1804856-76-5)
- Midazolam EP Impurity D (CAS 59468-83-6)
- 2-Chlorothiazol-5-amine (CAS 1257854-72-0)
- Glucagon receptor antagonists-2 (CAS 202917-18-8)
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