1H-Indole-2,6-bis(carboximidamide) dihydrochloride CAS 72998-90-4
| CAS No. | 72998-90-4 |
| Molecular Formula | C10H11N5 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1H-Indole-2,6-bis(carboximidamide) dihydrochloride (CAS 72998-90-4) is a high-purity analytical reference standard with the molecular formula C10H11N5HCl and a molecular weight of 237.69 g/mol.
The molecular framework of 1H-Indole-2,6-bis(carboximidamide) dihydrochloride (C10H11N5HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 1H-Indole-2,6-bis(carboximidamide) dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11N5 HCl |
| Molecular Weight | 237.69 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related H Standards
- 1H-Indole-2,4,6-tricarboxylic acid (CAS 1000341-50-3)
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- Indole-3-butyryl-L-leucine (CAS 1009593-81-0)
- Methyl Indole-5-Carboxylate (CAS 1011-65-0)
- Indole-3-butyryl-L-aspartic Acid (CAS 101289-65-0)
- 1H-Indole-3-acetamide, 5-chloro-α-oxo- (CAS 1016-35-9)
- 1H-Indole-6-carbaldehyde oxime (CAS 1018038-62-4)
Recommended Standards
- 4-(But-3-en-1-yl)-6-chloropyrimidine (CAS 2092564-33-3)
- 5-Ethyl-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 136562-04-4)
- Benzenesulfonic acid, (acetylamino)- (CAS 138721-63-8)
- 1-(5-Cyclopropyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)pyrrolidine-3-carboxylic acid (CAS 1707399-06-1)
- Lidocaine Impurity 97 (CAS CATO-C4X-167997)
- 4-{[5-({[(3-Fluorobenzyl)oxy]imino}methyl)-2-pyridinyl]oxy}benzenecarbonitrile (CAS 339014-82-3)
- 1-(6-Fluoro-4-methylpyridin-3-yl)ethan-1-one (CAS 1393562-90-7)
- 5-Chloro-2-cyano-3-methylpyridine (CAS 156072-84-3)
- (E)-N-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]({4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl})methylidene}hydroxylamine (CAS 320420-34-6)
- Tirzepatide Impurity 23 X TFA Salt (CAS CATO-C4X-324023)
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