Phentolamine Hydrochloride CAS 73-05-2
| CAS No. | 73-05-2 |
| Molecular Formula | C17H19N3O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Phentolamine Hydrochloride (CAS 73-05-2) is a high-purity analytical reference standard with the molecular formula C17H19N3OHCl and a molecular weight of 317.82 g/mol.
Phentolamine Hydrochloride (C17H19N3OHCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H19N3O HCl |
| Molecular Weight | 317.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Phentolamine Standards
- Phentolamine Mesilate Impurity 6 (CAS 13338-49-3)
- Phentolamine-d4 HCl (Regitine-d4 HCl) (CAS 1346599-65-2)
- Phentolamine Mesilate EP Impurity A (CAS 2724727-52-8（free base）)
- Phentolamine Impurity 8 (CAS 2767988-83-8)
- Phentolamine Impurity 9 (CAS 4284-47-3)
- Phentolamine (CAS 50-60-2)
- Phentolamine Impurity 17 (CAS 57182-48-6)
- Phentolamine Mesilate EP Impurity C (CAS 61537-49-3)
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