2-[2-(chloromethyl)-4-oxo-3,4-dihydroquinazolin-3-yl]acetonitrile CAS 730992-44-6
| CAS No. | 730992-44-6 |
| Molecular Formula | C11H8ClN3O |
| Molecular Weight | 233.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-[2-(chloromethyl)-4-oxo-3,4-dihydroquinazolin-3-yl]acetonitrile (CAS 730992-44-6), molecular formula C11H8ClN3O and molecular weight 233.65 g/mol, is a CATO reference standard with documented purity and traceability.
2-[2-(chloromethyl)-4-oxo-3,4-dihydroquinazolin-3-yl]acetonitrile (C11H8ClN3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-[2-(chloromethyl)-4-oxo-3,4-dihydroquinazolin-3-yl]acetonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8ClN3O |
| Molecular Weight | 233.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related chloromethyl Standards
- 2-Chloromethyl-10H-benzo[4,5]imidazo[1,2-a]pyrimidin-4-one (CAS 62773-10-8)
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- 7-(chloromethyl)-5-oxo-4H,5H-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 869947-01-3)
- 2-(Chloromethyl)-6-benzyloxypyridine (CAS 123926-27-2)
- 2-(Chloromethyl)-4-methyl-2,3-dihydrofuro[3,2-c]quinoline (CAS 88571-62-4)
- 5-(Chloromethyl)-2-(4-methoxyphenyl)pyridine (CAS 886361-72-4)
- 6-(Chloromethyl)-2,3-dihydro-1H,5H-pyrido-[3,2,1-ij]quinolin-5-one (CAS 849021-07-4)
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Recommended Standards
- 2-[1-amino-2-(3-chlorophenoxy)ethylidene]malononitrile (CAS 343375-39-3)
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- 2-(5-Chlorofuran-2-yl)-1H-benzo[d]imidazol-5-amine (CAS 37128-76-0)
- 2-Chloro-4-(pyridin-4-yl)benzoic acid (CAS 216959-88-5)
- 3-Chloro-7-methyl-1-phenyl-5,6,7,8-tetrahydro-2,7-naphthyridine-4-carbonitrile (CAS 1447960-16-8)
- 1-((2-(Diethylamino)ethyl)thio)but-3-en-2-ol (CAS 39159-35-8)
- 135840-47-0 ACMC-20e658 Benzo[b]thiophene-3-carboxylic acid, 4,5,6,7-tetrahydro-, hydrazide (CAS 135840-47-0)
- 3-Chloro-N-3-pyridinylpropanamide hydrochloride (CAS 1609407-51-3)
- (2,2-Difluoro-3-phenylbicyclo[1.1.1]Pentan-1-yl)methanol (CAS 2381247-98-7)
- 2,2,2-Trifluoro-1-(5-methylfuran-2-yl)ethan-1-amine (CAS 1250563-61-1)
- 4-(Furan-2-yl)-6-(5-methylthiophen-2-yl)pyrimidin-2-amine (CAS 1354924-58-5)
- 3-Chloro-2-fluorobenzyl Bromide (CAS 85070-47-9)
- 7-Acety Baccatin III (CAS 32981-90-1)
- Hexapeptide-11 (CAS 161258-30-6)
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