8-(chloromethyl)-6-fluoro-2-phenyl-4H-1,3-benzodioxine CAS 730992-77-5
| CAS No. | 730992-77-5 |
| Molecular Formula | C15H12ClFO2 |
| Molecular Weight | 278.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
8-(chloromethyl)-6-fluoro-2-phenyl-4H-1,3-benzodioxine (C15H12ClFO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
8-(chloromethyl)-6-fluoro-2-phenyl-4H-1,3-benzodioxine (CAS 730992-77-5) is a high-purity analytical reference standard with the molecular formula C15H12ClFO2 and a molecular weight of 278.71 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 8-(chloromethyl)-6-fluoro-2-phenyl-4H-1,3-benzodioxine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H12ClFO2 |
| Molecular Weight | 278.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F/Cl-containing |
Related chloromethyl Standards
- 3-(Chloromethyl)-2-(4-(trifluoromethyl)phenyl)tetrahydro-2H-pyran (CAS 1522221-98-2)
- 3-(chloromethyl)-5-(4-phenyloxan-4-yl)-1,2,4-oxadiazole (CAS 1311316-70-7)
- 3-(Chloromethyl)-7-(2-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyrazin-8(7H)-one (CAS 1713462-20-4)
- 5-(Chloromethyl)-2-methanesulfonyl-1-[(oxolan-2-yl)methyl]-1h-imidazole (CAS 1221341-62-3)
- ethyl 4-(chloromethyl)-2-[(2-methoxyethyl)amino]-1,3-thiazole-5-carboxylate (CAS 937598-20-4)
- 5-(Chloromethyl)-1-hexyl-2-methanesulfonyl-1h-imidazole (CAS 1221341-20-3)
- 4-(chloromethyl)-2-(2,6-dichlorophenyl)-1,3-thiaZole (CAS 90877-03-5)
- 2-(Chloromethyl)-6-iodoisonicotinonitrile (CAS 1393543-18-4)
Recommended Standards
- 7-(4-Chlorophenyl)-5-hydroxybenzo[d][1,3]oxathiol-2-one (CAS 327078-55-7)
- Ethyl 3-(chlorosulfonyl)-4-methoxybenzoate (CAS 262589-79-7)
- 7-(3-Chloro-phenyl)-5-hydroxy-benzo[1,3]oxathiol-2-one (CAS 307514-06-3)
- Methyl 2-(4-(chlorosulfonyl)-2-methylphenoxy)acetate (CAS 56077-82-8)
- 2-Iodo-1,3-dimethyl-5-(trifluoromethyl)benzene (CAS 875550-67-7)
- 2,4,5,6-Tetrafluoropyridin-3-ol (CAS 74199-51-2)
- Furan-2-yl(3-methoxyphenyl)methanol (CAS 944523-02-8)
- Gemcitabine-13C-15N2 (CAS 1233921-74-8)
- 3-[(Cyclopropylmethyl)amino]-1-(4-methoxyphenyl)pyrrolidine-2,5-dione (CAS 1415719-08-2)
- [(2R,3S,5R)-5-(6-Aminopurin-9-yl-3-Hydroxyoxolan-2-Yl]Methyl 4-Fluorosulfonylbenzoate (CAS 126463-19-2)
- 2158-91-0 2-benzoyl-4-nitrobenzoic acid DTXSID80357867 (CAS 2158-91-0)
- 4-(Azetidin-1-yl)-6-chloropyrimidine (CAS 881401-67-8)
- ethyl (1S,3R,4R)-2-azabicyclo[2.2.1]heptane-3-carboxylate hydrochloride (CAS 229014-45-3)
- Semaglutide（sodium salt） (CAS CATO-C4X-222619)
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