2-(Trifluoromethyl)imidazo[1,2-a]pyrimidine CAS 73221-25-7
| CAS No. | 73221-25-7 |
| Molecular Formula | C7H4F3N3 |
| Molecular Weight | 187.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Trifluoromethyl)imidazo[1,2-a]pyrimidine.
2-(Trifluoromethyl)imidazo[1,2-a]pyrimidine (CAS 73221-25-7), molecular formula C7H4F3N3 and molecular weight 187.12 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-(Trifluoromethyl)imidazo[1,2-a]pyrimidine (C7H4F3N3) contains a nitrile group, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 187.12 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(Trifluoromethyl)imidazo[1,2-a]pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H4F3N3 |
| Molecular Weight | 187.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Trifluoromethyl Standards
- 8-(Trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine (CAS 1019025-18-3)
- 5-(Trifluoromethyl)imidazo[1,2-a]pyrimidine (CAS 1020033-87-7)
- 2-(Trifluoromethyl)imidazo[1,2-a]pyrazine (CAS 109113-96-4)
- 2-(Trifluoromethyl)imidazo[1,2-b]pyridazine (CAS 109114-00-3)
- 6-(Trifluoromethyl)-1H-pyrazolo[3,4-b]pyridine (CAS 1196153-90-8)
- 6-(Trifluoromethyl)-1H-pyrazolo[4,3-b]pyridine (CAS 1211589-93-3)
- 2-(4-(Trifluoromethyl)pyrimidin-2-yl)acetonitrile (CAS 1219483-61-0)
- 5-(Trifluoromethyl)pyrazolo[3,4-b]pyridine (CAS 1245914-99-1)
Recommended Standards
- 2-(Trifluoromethyl)benzo[d]oxazole (CAS 2008-04-0)
- 2,3,5-Trifluoro-4-methoxybenzonitrile (CAS 916791-82-7)
- 2-(Trifluoromethyl)-3H-imidazo[4,5-c]pyridine (CAS 19918-36-6)
- 2-Hydroxy-2-(3,4,5-trifluorophenyl)acetonitrile (CAS 357333-21-2)
- benzyl 4-hydroxy-2-(methoxymethyl)pyrrolidine-1-carboxylate (CAS 1909312-05-5)
- (E)-[(5-Bromo-1H-indol-3-yl)methylidene](prop-2-en-1-yloxy)amine (CAS 866155-76-2)
- 2-Methyl-5-(pyrrolidine-1-sulfonyl)benzoic acid (CAS 353467-90-0)
- 4-(4-ETHYL-PHENYL)-THIAZOL-2-YLAMINE (CAS 85112-35-2)
- 2-(Difluoromethyl)-3-(trifluoromethyl)pyridine-4-carbonyl chloride (CAS 1804446-63-6)
- 2-(3-Aminoazetidin-1-yl)-N-(3-methoxypropyl)acetamide (CAS 1342136-65-5)
- 2-Oxo-1-(triphenylmethyl)pyrrolidine-3-carboxylic acid (CAS 1951444-98-6)
- 1-(4-Bromo-2-nitrophenyl)-1,4-diazepane (CAS 1016837-21-0)
- Perindopril Impurity 106 (CAS CATO-C4X-1252106)
- Semaglutide Impurity 151 xTFA (CAS CATO-C4X-2226151)
Why CATO?
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