6-bromo-1,4-dioxaspiro[4.7]dodecane CAS 73274-50-7
| CAS No. | 73274-50-7 |
| Molecular Formula | C10H17BrO2 |
| Molecular Weight | 249.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 6-bromo-1,4-dioxaspiro[4.7]dodecane (CAS 73274-50-7), a certified reference material (molecular formula C10H17BrO2, MW 249.14 g/mol) for analytical method development and quality control.
The molecular framework of 6-bromo-1,4-dioxaspiro[4.7]dodecane (C10H17BrO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H17BrO2 |
| Molecular Weight | 249.14 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | Br-containing |
Related bromo Standards
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Recommended Standards
- 5-fluoro-2-(4-fluorophenyl)-4-(trifluoromethyl)-1,3-oxazole (CAS 83081-29-2)
- 3-Nitro-4-(2,2,2-trifluoroethoxy)benzaldehyde (CAS 959859-92-8)
- 8-Acetoxy-2-bromo-octene (CAS 731773-24-3)
- 3,5-Bis(chloromethyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole (CAS 252334-30-8)
- Diethylene Glycol Cyclic Phthalate (CAS 13988-26-6)
- 1-(2,3-Dihydro-1h-inden-5-yl)-2-(methylthio)ethan-1-one (CAS 1178464-41-9)
- 4-Bromo-3-ethylbenzo[d]isoxazole (CAS 1368048-13-8)
- 7-Hydroxybenzo[d]isoxazol-3(2H)-one (CAS 855996-67-7)
- Propranolol Impurity 43 (CAS CATO-C4X-151943)
- 1-Cyclohexyl-4-phenylquinazolin-2(1H)-one (CAS 50817-30-6)
- Degarelix Impurity 8 (CAS 2648486-38-6)
- 3-(4,4,6-trimethyl-1,3,2-dioxaborinan-2-yl)benzonitrile (CAS 934558-35-7)
- 2-(3-Chlorophenoxy)acetimidamide (CAS 170735-26-9)
- Myristoyl Pentapeptide-4 (CAS 1392416-25-9)
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