6-(tert-Butyldimethylsilyloxy)-1-hexyne CAS 73448-13-2

Purity 97%+In StockPharmaceutical Standards
CAS No.73448-13-2
Molecular FormulaC12H24OSi
Molecular Weight212.40 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-(tert-Butyldimethylsilyloxy)-1-hexyne CAS 73448-13-2 chemical structure

Description

6-(tert-Butyldimethylsilyloxy)-1-hexyne (CAS 73448-13-2), molecular formula C12H24OSi and molecular weight 212.40 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 6-(tert-Butyldimethylsilyloxy)-1-hexyne (C12H24OSi) is characterized by a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H24OSi
Molecular Weight212.40 g/mol
Purity97%+
StorageStore at room temperature
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityStable under recommended storage conditions
Degree of Unsaturation (DBE)1.0
CAS Registry Year (est.)1977

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