Methyl 4,5-Bis(chloromethyl)thiophene-2-carboxylate CAS 7353-89-1
| CAS No. | 7353-89-1 |
| Molecular Formula | C8H8Cl2O2S |
| Molecular Weight | 239.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Methyl 4,5-Bis(chloromethyl)thiophene-2-carboxylate (CAS 7353-89-1), molecular formula C8H8Cl2O2S and molecular weight 239.12 g/mol, is a CATO reference standard with documented purity and traceability.
Methyl 4,5-Bis(chloromethyl)thiophene-2-carboxylate (C8H8Cl2O2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Methyl 4,5-Bis(chloromethyl)thiophene-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8Cl2O2S |
| Molecular Weight | 239.12 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Recommended Standards
- Ethyl 2-(2,5-dichlorothiophen-3-yl)acetate (CAS 37784-66-0)
- Ticagrelor impurity 95 (CAS CATO-C4X-109395)
- Eletriptan Impurity 6 (CAS 3123-10-2)
- 2-Bromo-4-phenylthiophene (CAS 10353-18-1)
- 4-[(3,5-Dimethyl-1H-pyrazol-1-yl)methyl]piperidine dihydrochloride (CAS 1311317-19-7)
- 7-chloro-4-oxo-4H-chromene-3-carboxylic Acid (CAS 77202-50-7)
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- Tert-butyl 4-(2-oxo-5-phenyloxazolidin-3-yl)piperidine-1-carboxylate (CAS 521979-95-3)
- [a-Glu](Side chain transposition)- Semaglutide (CAS CATO-C4X-2226111)
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