2-Chloro-6-methoxyquinoline-3-carbaldehyde CAS 73568-29-3
| CAS No. | 73568-29-3 |
| Molecular Formula | C11H8ClNO2 |
| Molecular Weight | 221.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 2-Chloro-6-methoxyquinoline-3-carbaldehyde (CAS 73568-29-3), a certified reference material (molecular formula C11H8ClNO2, MW 221.64 g/mol) for analytical method development and quality control.
The molecular framework of 2-Chloro-6-methoxyquinoline-3-carbaldehyde (C11H8ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H8ClNO2 |
| Molecular Weight | 221.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 6-Chloro-4H-[1,3]dioxino[5,4-c]isoquinoline (CAS 106488-48-6)
- 4-Chloro-3-(1H-pyrrol-1-yl)benzoic acid (CAS 107946-72-5)
- 8-Chloro-2-methylquinoline-3-carboxylic acid (CAS 1089898-90-7)
- 7-Chloro-8-methylquinoline-2-carboxylic acid (CAS 1092305-25-3)
- 1-Acetyl-3-chloro-1H-indole-2-carbaldehyde (CAS 110912-14-6)
- 2-Chloro-3-(1-cyanocyclopropyl)benzoic acid (CAS 1123582-10-4)
- 4-Chloro-2-methylquinoline-7-carboxylic acid (CAS 1150618-20-4)
- N-[(4-chloro-1-phenyl-1H-imidazol-5-yl)methylidene]hydroxylamine (CAS 1181480-96-5)
Recommended Standards
- 2-chloro-5-(1H-pyrrol-1-yl)benzoic acid (CAS 53242-68-5)
- 2-Chloro-6-methylquinoline-4-carboxylic acid (CAS 50503-75-8)
- 2-Chloro-4-methylquinoline-3-carboxylic acid (CAS 773100-20-2)
- 2-Chloro-7-methoxyquinoline-3-carbaldehyde (CAS 68236-20-4)
- 2,5-Difluoro-1-methyl-3-nitrobenzene (CAS 1093758-82-7)
- 8-Bromo-indolizine-3-carboxylic acid ethyl ester (CAS 1823961-62-1)
- 2-Amino-4,6-dimethylphenol (CAS 41458-65-5)
- Dimethyl 2-(2,2-diethoxyethyl)malonate (CAS 906652-81-1)
- (2,4-Dibromo-6-(difluoromethoxy)phenyl)(methyl)sulfane (CAS 1805121-02-1)
- Methyl 4-hydroxy-5,6-dihydro-2H-pyran-3-carboxylate (CAS 910332-88-6)
- Z-Arg-OH · HCl (CAS 56672-63-0)
- 3-((4-Methoxyphenyl)thio)propane-1-sulfonyl chloride (CAS 1375067-78-9)
- Boc-Tyr(Me)-OH (CAS 53267-93-9)
- Tirzepatide Impurity 49 (CAS CATO-C4X-324049)
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