N-(5-Acetyl-4-methylthiazol-2-yl)-2-(thiophen-2-yl)acetamide CAS 736167-89-8

Purity 97%+In StockPharmaceutical Standards
CAS No.736167-89-8
Molecular FormulaC12H12N2O2S2
Molecular Weight280.37 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(5-Acetyl-4-methylthiazol-2-yl)-2-(thiophen-2-yl)acetamide CAS 736167-89-8 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(5-Acetyl-4-methylthiazol-2-yl)-2-(thiophen-2-yl)acetamide.

N-(5-Acetyl-4-methylthiazol-2-yl)-2-(thiophen-2-yl)acetamide (CAS 736167-89-8) is a high-purity analytical reference standard with the molecular formula C12H12N2O2S2 and a molecular weight of 280.37 g/mol.

The molecular framework of N-(5-Acetyl-4-methylthiazol-2-yl)-2-(thiophen-2-yl)acetamide (C12H12N2O2S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(5-Acetyl-4-methylthiazol-2-yl)-2-(thiophen-2-yl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H12N2O2S2
Molecular Weight280.37 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1986
Nitrogen Atoms2
Sulfur Atoms2

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