Norepinephrine Impurity 102 CAS 737691-58-6
| CAS No. | 737691-58-6 |
| Molecular Formula | C10H15NO3 |
| Molecular Weight | 197.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Norepinephrine Impurity 102 is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Norepinephrine Impurity 102 (CAS 737691-58-6), a pharmacopoeial impurity reference standard (molecular formula C10H15NO3, MW 197.23 g/mol) used for the identification and quantification of trace impurities in APIs.
Norepinephrine Impurity 102 (C10H15NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H15NO3 |
| Molecular Weight | 197.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 1 |
Related Norepinephrine Standards
- Norepinephrine Impurity 103 (CAS 102743-86-2)
- Norepinephrine Impurity 113 (CAS CATO-C4X-1514113)
- Norepinephrine Impurity 83 (CAS CATO-C4X-151483)
- Norepinephrine EP Impurity F (CAS 103-49-1)
- Norepinephrine Impurity 162 (CAS CATO-C4X-1514162)
- Norepinephrine Impurity 31 (CAS CATO-C4X-1514131)
- Norepinephrine Impurity 23 (CAS 14771-02-9)
- Norepinephrine Impurity 25 (CAS 17345-68-5)
Recommended Standards
- (1R,5R,6R)-8-methyl-3-oxo-8-azabicyclo[3.2.1]octan-6-yl acetate (CAS CATO-C4X-148961)
- Nafamostat impurity 78 (CAS 66217-26-3)
- 3-Hydroxy-3-azaspiro[5.5]undecane-2,4-dione (CAS 64744-41-8)
- Agomelatine Impurity 15 (CAS 138113-08-3)
- Ilaprazole impurity 182 (CAS CATO-C4X-1130182)
- Raltitrexed Impurity 43 (CAS CATO-C4X-138643)
- Caspofungin Impurity 31(5-((3R)-3-Hydroxy-L-Ornithine)-Pneumocandin B0) (CAS 150283-04-8)
- 2-(1-Methylcyclopropyl)ethanamine (CAS 62441-59-2)
- 2-Bromopropanedinitrile (CAS 1885-22-9)
- tert-Butyl 3-amino-4,4-dimethylpiperidine-1-carboxylate (CAS 1498964-85-4)
- 4-Bromo-2-(N-isopropylamino)pyridine (CAS 1209458-03-6)
- (5-Iodothiophen-3-yl)(morpholino)methanone (CAS 1355932-10-3)
- 2-(4-Fluorophenyl)-1,3,8-triazaspiro[4.5]Dec-2-en-4-one (CAS 1707580-74-2)
- Atrial Natriuretic Peptide (ANP)(1-28) Alpha (Human, Ovine, Canine) (CAS 91917-63-4)
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