Methyl 3-hydroxyquinoline-4-carboxylate CAS 73776-18-8
| CAS No. | 73776-18-8 |
| Molecular Formula | C11H9NO3 |
| Molecular Weight | 203.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl 3-hydroxyquinoline-4-carboxylate (CAS 73776-18-8), molecular formula C11H9NO3 and molecular weight 203.19 g/mol, is a CATO reference standard with documented purity and traceability.
Methyl 3-hydroxyquinoline-4-carboxylate (C11H9NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 3-hydroxyquinoline-4-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H9NO3 |
| Molecular Weight | 203.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- Methyl 6-hydroxyquinoline-5-carboxylate (CAS 104612-29-5)
- Methyl 7-hydroxyquinoline-4-carboxylate (CAS 1260825-38-4)
- 4-Hydroxyquinoline-6-acetic acid (CAS 1261543-45-6)
- Methyl 3-hydroxyquinoline-6-carboxylate (CAS 1261596-90-0)
- 4-Hydroxyquinoline-8-acetic acid (CAS 1261631-50-8)
- Methyl 7-hydroxyquinoline-8-carboxylate (CAS 1261636-70-7)
- Methyl 6-hydroxyquinoline-3-carboxylate (CAS 1261740-91-3)
- Methyl 6-hydroxyquinoline-8-carboxylate (CAS 1261813-51-7)
Recommended Standards
- Methyl 3-cyano-2-oxo-3-phenylpropanoate (CAS 397887-10-4)
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- Methyl 4-(2-Cyanoacetyl)benzoate (CAS 69316-08-1)
- 2-azabicyclo[2.2.1]heptan-5-one;hydrochloride (CAS 1785396-17-9)
- (S)-2',3',4',9'-Tetrahydrospiro[oxetane-3,1'-pyrido[3,4-b]indole]-3'-carboxylic acid (CAS 1956436-34-2)
- 8-((4-(2-Hydroxyethyl)piperazin-1-yl)methyl)-7-(3-hydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione (CAS 851941-48-5)
- 4-((3-Bromobenzylidene)amino)-3-(3-chlorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 478254-61-4)
- 1,6,7-Trichloroisoquinoline (CAS 1378260-88-8)
- N-Cyclopropyl-3-methyl-2,3-dihydro-1H-inden-1-amine (CAS 1220039-96-2)
- Marimastat (CAS 154039-60-8)
- 1-(3-Methoxyphenyl)-1-phenylethanol (CAS 94001-64-6)
- 3-(4,4,4-Trifluoro-3-oxobutanoyl)benzonitrile (CAS 846601-25-0)
- Semaglutide impurity 43 (CAS CATO-C4X-222643)
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