4-((4-Bromobenzyl)oxy)quinazoline CAS 737818-56-3
| CAS No. | 737818-56-3 |
| Molecular Formula | C15H11BrN2O |
| Molecular Weight | 315.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-((4-Bromobenzyl)oxy)quinazoline (CAS 737818-56-3), molecular formula C15H11BrN2O and molecular weight 315.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-((4-Bromobenzyl)oxy)quinazoline (C15H11BrN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H11BrN2O |
| Molecular Weight | 315.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromobenzyl Standards
- 3-(4-Bromobenzyl)-5-phenyl-1,2,4-oxadiazole (CAS 1345020-60-1)
- 3-(4-Bromobenzyl)quinazolin-4(3H)-one (CAS 302913-19-5)
- (3-Bromobenzyl)(3,4-difluorophenyl)sulfane (CAS 1281219-33-7)
- (4-Bromobenzyl)(3,4-difluorophenyl)sulfane (CAS 1443302-70-2)
- (4-Bromobenzyl)(3,5-difluorophenyl)sulfane (CAS 1443345-47-8)
- (3-Bromobenzyl)(3,5-difluorophenyl)sulfane (CAS 1443345-56-9)
- (2-Bromobenzyl)(3,5-difluorophenyl)sulfane (CAS 1443347-52-1)
- (2-Bromobenzyl)(3,4-difluorophenyl)sulfane (CAS 1443353-06-7)
Recommended Standards
- 3-Bromo-4-phenyl-1,3-dihydro-2h-1,5-benzodiazepin-2-one (CAS 66752-03-2)
- 4-(2-(4-Bromophenyl)oxazol-5-yl)aniline (CAS 89752-98-7)
- 3-Bromo-4-methoxy-N-methyl-N-(2-(methylamino)-2-oxoethyl)benzamide (CAS 941103-81-7)
- 4-(4-Bromophenyl)-1-phenyl-1,3-dihydro-2H-imidazol-2-one (CAS 688057-69-4)
- 2-[(ethylamino)methyl]-3,4-dihydroquinazolin-4-one (CAS 143993-13-9)
- Maltol Related Compound 2 (CAS 243987-44-2)
- 5-Methyl-N,1-bis(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxamide (CAS 321431-48-5)
- tert-Butyl N-[(1-aminocyclobutyl)methyl]carbamate (CAS 1403767-13-4)
- p-Iodoclonidine HCl (CAS 108294-57-1)
- 1-(Bromomethyl)-1-isobutoxycyclopentane (CAS 1247864-32-9)
- 5-(tert-Butyl)isoxazole-3-carboxylic Acid (CAS 90607-21-9)
- Osimertinib Impurity 70 (CAS CATO-C4X-204570)
- 5-(Allyloxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde (CAS 303151-60-2)
- Glucagon (1-29) (CAS 16941-32-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com