2,3-Bis(trifluoromethyl)pyrazolo[1,5-a]pyridine CAS 73883-19-9
| CAS No. | 73883-19-9 |
| Molecular Formula | C9H4F6N2 |
| Molecular Weight | 254.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2,3-Bis(trifluoromethyl)pyrazolo[1,5-a]pyridine (CAS 73883-19-9), molecular formula C9H4F6N2 and molecular weight 254.13 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,3-Bis(trifluoromethyl)pyrazolo[1,5-a]pyridine (C9H4F6N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2,3-Bis(trifluoromethyl)pyrazolo[1,5-a]pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H4F6N2 |
| Molecular Weight | 254.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Bis Standards
- 2,5-Bis(trifluoromethyl)-1H-benzo[d]imidazole (CAS 399-69-9)
- 2,7-Bis(trifluoromethyl)-1H-benzo[d]imidazole (CAS 392-36-9)
- 4,7-Bis(trifluoromethyl)-1H-benzo[d]imidazole (CAS 81769-74-6)
- 5,7-Bis(trifluoromethyl)imidazo[1,2-a]pyridine (CAS 882747-98-0)
- 8-(Trifluoromethyl)isoxazolo[4,3-c]quinolin-3(1H)-one (CAS 1315343-14-6)
- 1-(Trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxalin-4-ol (CAS 91895-67-9)
- 1-(5-(2-(Trifluoromethyl)phenyl)furan-2-yl)ethanone (CAS 1157857-87-8)
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Recommended Standards
- 2-(Azulen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 620634-44-8)
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- 1-[(1e)-2-(4-bromophenyl)diazen-1-yl]pyrrolidine (CAS 250160-26-0)
- 2,4-Dichloro-N-ethylbenzenesulfonamide (CAS 886123-03-1)
- [[(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)sulfonyl](4-methylphenyl)amino]acetic acid (CAS 899718-62-8)
- STF 083010 (CAS 307543-71-1)
- 2-Methyl-2-(2-nitrophenyl)propanoyl chloride (CAS 1056427-10-1)
- 3-bromo-4-phenyl-3,4-dihydro-2H-[1,3]thiazino[3,2-a]benzimidazole (CAS 750570-81-1)
- 5-Methyl-N-(3-(trifluoromethyl)phenyl)isoxazole-3-carboxamide (CAS 646530-36-1)
- Ethyl 6-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinate (CAS 2096337-57-2)
- 2-{[1-(4-Methylphenyl)-1H-pyrazol-4-yl]carbonyl}phenyl 2-thiophenecarboxylate (CAS 955964-93-9)
- 4-(MEthylamino)phenol xsulfate (CAS 1936-57-8)
- Topiroxostat Impurity 5 (CAS 6975-73-1)
- [α-Glu](Sidechain trans-position)-Liraglutide (CAS CATO-C4X-199240)
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