6-Amino-5-(4-chlorobenzyl)pyrimidine-2,4(1H,3H)-dione CAS 73908-08-4
| CAS No. | 73908-08-4 |
| Molecular Formula | C11H10ClN3O2 |
| Molecular Weight | 251.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Amino-5-(4-chlorobenzyl)pyrimidine-2,4(1H,3H)-dione.
6-Amino-5-(4-chlorobenzyl)pyrimidine-2,4(1H,3H)-dione (CAS 73908-08-4), molecular formula C11H10ClN3O2 and molecular weight 251.67 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Amino-5-(4-chlorobenzyl)pyrimidine-2,4(1H,3H)-dione (C11H10ClN3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Amino-5-(4-chlorobenzyl)pyrimidine-2,4(1H,3H)-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10ClN3O2 |
| Molecular Weight | 251.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- Methyl 5-amino-1-(3-chlorophenyl)-1H-pyrazole-4-carboxylate (CAS 121716-20-9)
- Methyl 5-amino-1-(4-chlorophenyl)-1H-pyrazole-4-carboxylate (CAS 121716-21-0)
- Methyl 5-amino-1-(2-chlorophenyl)-1H-pyrazole-4-carboxylate (CAS 1264044-28-1)
- 5-Amino-1-(4-chlorobenzyl)-1h-1,2,3-triazole-4-carboxamide (CAS 132269-38-6)
- 2-Amino-4-chloro-N-(3-methylisoxazol-5-yl)benzamide (CAS 144485-94-9)
- 6-Amino-1-[(4-chlorophenyl)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 179486-47-6)
- 4-Amino-3-((4-chlorophenyl)amino)-6-methyl-1,2,4-triazin-5(4H)-one (CAS 22285-10-5)
- 5-Amino-1-(3-chloro-4-methylphenyl)-1H-1,2,3-triazole-4-carboxamide (CAS 887689-38-5)
Recommended Standards
- 6-Amino-1-benzyl-5-chloropyrimidine-2,4(1H,3H)-dione (CAS 343347-98-8)
- 6-chloro-1-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 66176-24-7)
- 6-Amino-1-(4-chlorophenyl)-3-methylpyrimidine-2,4(1H,3H)-dione (CAS 7629-18-7)
- 8-Chloro-1-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 51395-55-2)
- 1-(3-(2-Methoxyethyl)-1,2,4-oxadiazol-5-yl)-3-(methylthio)propan-1-amine (CAS 1239841-45-2)
- N-(Pyridin-3-yl)morpholine-4-sulfonamide (CAS 838888-48-5)
- 1,6-Dimethylnaphthalen-2-ol (CAS 17324-10-6)
- 1242925-47-8 1-(2-Aminoethyl)-N,N-dimethyl-1H-1,2,3-benzotriazole-5-sulfonamide MFCD15732383 (CAS 1242925-47-8)
- 1-(tert-Butyl) 2-methyl (2R,3S)-3-fluoropyrrolidine-1,2-dicarboxylate (CAS 926910-53-4)
- 2-{[2-(piperidin-1-yl)-1,3-thiazol-5-yl]methylidene}-2,3-dihydro-1H-indene-1,3-dione (CAS 860784-45-8)
- N-cyclopropyl-4-hydrazinylbenzene-1-sulfonamide (CAS 1153316-84-7)
- 4,4,5,5-Tetramethyl-2-(2-(trifluoromethyl)thiophen-3-yl)-1,3,2-dioxaborolane (CAS 2246611-07-2)
- (R)-tert-Butyl 3-(aminomethyl)morpholine-4-carboxylate oxalate (CAS 1956436-20-6)
- [Glu]17-Semaglutide (CAS CATO-CPTD788604)
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