2-Bromo-4-(chloromethyl)thiophene CAS 73919-92-3
| CAS No. | 73919-92-3 |
| Molecular Formula | C5H4BrClS |
| Molecular Weight | 211.51 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Bromo-4-(chloromethyl)thiophene (C5H4BrClS) is characterized by sulfur-containing functionality, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-Bromo-4-(chloromethyl)thiophene (CAS 73919-92-3) is a high-purity analytical reference standard with the molecular formula C5H4BrClS and a molecular weight of 211.51 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Bromo-4-(chloromethyl)thiophene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H4BrClS |
| Molecular Weight | 211.51 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl/Br-containing |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 5-Bromo-2-chloro-3-methylthiophene (CAS 1182346-30-0)
- 4-Bromo-2-(chloromethyl)thiophene (CAS 170859-70-8)
- 2-Bromo-5-(chloromethyl)thiophene (CAS 7311-46-8)
- 2-Bromo-5-chloro-3-methylthiophene (CAS 53374-61-1)
- 3-Bromo-2-(chloromethyl)thiophene (CAS 7353-88-0)
- 3-Bromo-4-(chloromethyl)thiophene (CAS 70260-08-1)
- 3-Bromo-5-chloro-2-methylthiophene (CAS 61074-71-3)
- 1-bromo-2-(chloromethyl)benzene (CAS 578-51-8)
Recommended Standards
- 2-(Bromomethyl)-5-chlorothiophene (CAS 59311-22-7)
- 2-(Bromomethyl)-4-chlorothiophene (CAS 1400991-44-7)
- 3-(bromomethyl)-2-chlorothiophene (CAS 40032-81-3)
- n-Dodecyl-d25 Alcohol (CAS 160776-83-0)
- [2-(2-Methyl-1-piperidinyl)-3-pyridinyl]-methanamine (CAS 953737-44-5)
- Methyl Oxane-3-carboxylate (CAS 18729-20-9)
- 7-Bromo-3-methyl-1H-indole hydrate (CAS 853355-96-1)
- 2-Ethynyl-1-fluoro-4-(trifluoromethyl)benzene (CAS 1263377-27-0)
- 207300-90-1 Sodium 1-heptanesulfonate monohydrate MFCD00149550 1-Heptanesulfonic acid, sodium salt (1:1) 1-Heptanesulfonic acid, sodium salt (CAS 207300-90-1)
- 2-[methyl(trideuteriomethyl)amino]acetic acid (CAS 1219908-65-2)
- 3-(Dimethylamino)-1-(4-nitrophenyl)-2-propen-1-one (CAS 68760-11-2)
- N'-((5-(Dimethylamino)furan-2-yl)methylene)acetohydrazide (CAS 444674-29-7)
- 3-(Thiophen-2-yl)-1H-pyrazol-4-amine (CAS 158077-95-3)
- Semaglutide impurity 99 (CAS CATO-C4X-222699)
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