Sofosbuvir Impurity 95 CAS 7392-74-7
| CAS No. | 7392-74-7 |
| Molecular Formula | C27H22O8 |
| Molecular Weight | 474.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Sofosbuvir Impurity 95 (CAS 7392-74-7), a pharmacopoeial impurity reference standard (molecular formula C27H22O8, MW 474.46 g/mol) used for the identification and quantification of trace impurities in APIs.
Sofosbuvir Impurity 95 (C27H22O8) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Sofosbuvir Impurity 95 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H22O8 |
| Molecular Weight | 474.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
Related Sofosbuvir Standards
- Sofosbuvir Impurity 69 (CAS 863329-65-1)
- Sofosbuvir Impurity 100 (CAS CATO-C4X-1052100)
- Sofosbuvir Impurity 101 (CAS CATO-C4X-1052101)
- Sofosbuvir Impurity 8 (CAS 1910099-11-4)
- Sofosbuvir Impurity 8 (CAS 944476-44-2)
- Sofosbuvir Impurity 98 (CAS CATO-C4X-105298)
- Sofosbuvir Impurity 17 (CAS 1496551-71-3)
- Sofosbuvir Impurity 62 (CAS CATO-C4X-105262)
Recommended Standards
- Ribonic acid, 2-C-methyl-, γ-lactone, 2,3,5-tribenzoate (CAS 93636-17-0)
- Dexamethasone Sodium Phosphate EP Impurity H (CAS 162968-22-1)
- D-Arabinonic acid 2-C-methyl- γ-lactone 2,3,5-tribenzoate (CAS 93635-77-9)
- Dexamethasone impurity 93 (CAS 2414-45-1)
- Brexpiprazole Impurity 32 (CAS 5118-13-8)
- Dapagliflozin Impurity 84 (CAS CATO-C4X-113884)
- Abemaciclib Impurity 162 (CAS CATO-C4X-2937162)
- Ethyl 1-isopropyl-4-nitro-1H-pyrazole-5-carboxylate (CAS 1356543-32-2)
- 3-((2-Methyl-2-(methylthio)propyl)amino)thietane 1,1-dioxide (CAS 1856353-31-5)
- 4-(Aminomethyl)-n-ethylbenzenesulfonamide (CAS 402925-22-8)
- 2-Amino-1-(1-phenyl-1h-pyrazol-4-yl)ethan-1-one (CAS 1521074-57-6)
- 7-Isopropoxy-2-oxo-2H-chromene-3-carboxylic acid (CAS 914203-21-7)
- 2-(Aminomethyl)pyrimidine-5-carboxylic acid hydrochloride (CAS 2044713-83-7)
- Glu17-Semaglutide (CAS CATO-C4X-2226209)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com