3-(5-(Benzyloxy)-1H-indol-3-yl)propanoic acid CAS 7394-76-5
| CAS No. | 7394-76-5 |
| Molecular Formula | C18H17NO3 |
| Molecular Weight | 295.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(5-(Benzyloxy)-1H-indol-3-yl)propanoic acid (CAS 7394-76-5), molecular formula C18H17NO3 and molecular weight 295.33 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(5-(Benzyloxy)-1H-indol-3-yl)propanoic acid (C18H17NO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H17NO3 |
| Molecular Weight | 295.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Nitrogen Atoms | 1 |
Related Benzyloxy Standards
- 2-(5-(Benzyloxy)-2-methyl-1H-indol-3-yl)acetic acid (CAS 101734-29-6)
- 3-[6-(benzyloxy)-1h-indol-1-yl]propanoic acid (CAS 1219551-00-4)
- 6-(Benzyloxy)-1-ethyl-1h-indole-2-carboxylic acid (CAS 1240568-01-7)
- 2-(5-(Benzyloxy)-6-methyl-1H-indol-3-yl)acetic acid (CAS 1417984-61-2)
- N-((benzyloxy)carbonyl)-O-(tert-butyl)serine (CAS 14464-36-9)
- Methyl 4-(benzyloxy)-1-methyl-1H-indole-2-carboxylate (CAS 167479-10-9)
- 4-(benzyloxy)-5-methoxy-1-methyl-1H-indole-2-carbaldehyde (CAS 170034-67-0)
- 2-Benzyloxy-3-tert-butoxycarbonylamino-propionicacid (CAS 294858-36-9)
Recommended Standards
- 3-(4-Fluorophenyl)-7-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidine (CAS 861209-72-5)
- 3-(5,6-Dimethyl-1H-indol-2-yl)-4-methoxybenzoic acid (CAS 835595-03-4)
- 3-(2-Morpholino-2-oxoethyl)-1,3-diazaspiro[4.5]decane-2,4-dione (CAS 733791-48-5)
- 3-(5-Amino-4-(4-fluorophenyl)-1H-pyrazol-1-yl)tetrahydrothiophene 1,1-dioxide (CAS 321574-18-9)
- Magnesium Valproate (CAS 62959-43-7)
- Ethyl 3-(5-(2-nitrophenyl)furan-2-yl)acrylate (CAS 886496-61-3)
- 1-piperidin-4-yl-1H-benzimidazole,HCl (CAS 83763-11-5)
- Dapagliflozin Impurity 88 (CAS CATO-C4X-113888)
- (1r,2s,4s)-rel-norbornane-2-carboxylicacid (CAS 934-28-1)
- 3-methylcyclopentan-1-amine (CAS 52430-83-8)
- 3,4-(Isopropylidenedioxy) Shikimic Acid Methyl Ester Acetate (CAS 143308-74-1)
- (3AR,4S,6R,6aS)-6-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxole-4-carbaldehyde (CAS 1379540-71-2)
- Disodium Etidronate Hydrate (CAS 656253-47-3)
- Semaglutide impurity 43 (CAS CATO-C4X-222643)
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