73987-37-8 3-Quinolinecarboxylic acid, 8-chloro-4-hydroxy-, ethyl ester 4-22-00-02266 (Beilstein Handbook Reference) BRN 0219639 Ethyl 8-chloro-4-hydroxy-3-quinolinecarboxylate NSC 102517 CAS 73987-37-8

Purity 97%+In StockPharmaceutical Standards
CAS No.73987-37-8
Molecular FormulaC12H20ClNO3
Molecular Weight261.75 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

73987-37-8 3-Quinolinecarboxylic acid, 8-chloro-4-hydroxy-, ethyl ester 4-22-00-02266 (Beilstein Handbook Reference) BRN 0219639 Ethyl 8-chloro-4-hydroxy-3-quinolinecarboxylate NSC 102517 CAS 73987-37-8 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

73987-37-8 3-Quinolinecarboxylic acid, 8-chloro-4-hydroxy-, ethyl ester 4-22-00-02266 (Beilstein Handbook Reference) BRN 0219639 Ethyl 8-chloro-4-hydroxy-3-quinolinecarboxylate NSC 102517 (CAS 73987-37-8) is a high-purity analytical reference standard with the molecular formula C12H20ClNO3 and a molecular weight of 261.75 g/mol.

The molecular framework of 73987-37-8 3-Quinolinecarboxylic acid, 8-chloro-4-hydroxy-, ethyl ester 4-22-00-02266 (Beilstein Handbook Reference) BRN 0219639 Ethyl 8-chloro-4-hydroxy-3-quinolinecarboxylate NSC 102517 (C12H20ClNO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H20ClNO3
Molecular Weight261.75 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1978
Halogen ContentCl-containing
Nitrogen Atoms1

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