2-((2-Hydroxynaphthalen-1-yl)methylene)hydrazine-1-carbothioamide CAS 7410-40-4

Description

Compared with other compounds in its class, the molecular weight of 245.30 g/mol gives 2-((2-Hydroxynaphthalen-1-yl)methylene)hydrazine-1-carbothioamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-((2-Hydroxynaphthalen-1-yl)methylene)hydrazine-1-carbothioamide (CAS 7410-40-4), molecular formula C12H11N3OS and molecular weight 245.30 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-((2-Hydroxynaphthalen-1-yl)methylene)hydrazine-1-carbothioamide (C12H11N3OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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