Fluticasone Impurity 65 CAS 74131-81-0
| CAS No. | 74131-81-0 |
| Molecular Formula | C21H24F2O5 |
| Molecular Weight | 394.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Fluticasone Impurity 65 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Fluticasone Impurity 65 (CAS 74131-81-0) is a certified pharmaceutical impurity reference standard with the molecular formula C21H24F2O5 and a molecular weight of 394.41 g/mol.
Based on its molecular formula C21H24F2O5, Fluticasone Impurity 65 contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 394.41 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C21H24F2O5 |
| Molecular Weight | 394.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F-containing |
Related Fluticasone Standards
- Fluticasone Impurity 60 (CAS CATO-C4X-165060)
- Fluticasone Impurity 86 (CAS CATO-C4X-165086)
- Fluticasone Impurity 56 (CAS CATO-C4X-165056)
- Fluticasone Propionate USP Related Compound J (CAS 28416-82-2)
- Fluticasone Impurity N10 (CAS 23961-95-7)
- Fluticasone Impurity 78 (CAS CATO-C4X-165078)
- Fluticasone Impurity 80 (CAS CATO-C4X-165080)
- Fluticasone Impurity 56 (CAS 28416-84-4)
Recommended Standards
- (2Z)-2-({3-methoxy-4-[(4-nitrophenyl)methoxy]phenyl}methylidene)-4,4-dimethyl-3-oxopentanenitrile (CAS 1013252-85-1)
- Tadalafil-13C2,d3 (CAS CATO-C4X-108754)
- tert-Butyl (2S,4R)-2-(bromomethyl)-4-((tert-butyldimethylsilyl)oxy)pyrrolidine-1-carboxylate (CAS 1017060-91-1)
- Ethyl 2-((6-benzyl-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)propanoate (CAS 674805-46-0)
- Relugolix Impurity 199 (CAS CATO-C4X-2429199)
- Diltiazem Impurity 16 (CAS 3036581-85-5)
- Ciprofloxacin Impurity 28 (CAS CATO-C4X-136228)
- (2-Methyl-6-pyrrolidin-2-yl-pyrimidin-4-yl)-(5-methyl-thiazol-2-yl)-amine hydrochloride (CAS 1361116-58-6)
- 4-[2-(4-Methoxy-4-methylpentan-2-ylidene)hydrazin-1-yl]-2,6-dimethylpyrimidine (CAS 1955564-17-6)
- 3-(2-(Ethylamino)propyl)-1,2,3,4-tetrahydro-5H-chromeno[3,4-c]pyridin-5-one (CAS 86371-40-6)
- 7-Chloro-1-iodonaphthalene (CAS 70109-79-4)
- 1-(1-(3-Phenyl-1,2,4-oxadiazol-5-yl)cyclohexyl)-3-(o-tolyl)urea (CAS 1396794-97-0)
- Lunularic acid (CAS 23255-59-6)
- Des-His(1)-Semaglutide (CAS CATO-C4X-2226216)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com