Pipecuronium bromide impurity 1 CAS 74133-45-2
| CAS No. | 74133-45-2 |
| Molecular Formula | C31H58N4O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Pipecuronium bromide impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Pipecuronium bromide impurity 1 (CAS 74133-45-2, C31H58N4O2Br) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Pipecuronium bromide impurity 1 (C31H58N4O2Br) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C31H58N4O2 2*Br |
| Molecular Weight | 598.73 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
Related Pipecuronium Standards
Recommended Standards
- Mavacoxib Impurity 5 (CAS CATO-C4X-30595)
- Niraparib Impurity 30 (CAS CATO-C4X-232930)
- Mavacamten Impurity 14 (CAS CATO-C4X-298214)
- 1-(4-Isobutoxy-3-methoxybenzyl)piperazine (CAS 523981-38-6)
- MY33-3 (hydrochloride) (CAS 2204280-42-0)
- 2-Methylthio-6-chloropurine riboside (CAS 66212-83-7)
- 5-Bromo-N,N,4-trimethylpyridin-2-amine (CAS 764651-68-5)
- 9-(Tert-butyl) 3-ethyl 2-oxo-9-azabicyclo[3.3.1]nonane-3,9-dicarboxylate (CAS 2414413-41-3)
- 4-Cyclopropylaniline (CAS 3158-71-2)
- PACAP-Related Peptide (PRP), rat (CAS 132769-35-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com