8-Hydroxy-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid CAS 74145-11-2
| CAS No. | 74145-11-2 |
| Molecular Formula | C11H12O3 |
| Molecular Weight | 192.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 8-Hydroxy-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid (CAS 74145-11-2), a certified reference material (molecular formula C11H12O3, MW 192.21 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, 8-Hydroxy-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 192.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H12O3 |
| Molecular Weight | 192.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
Related Hydroxy Standards
- (S)-2-(5-hydroxy-2,3-dihydro-1H-inden-1-yl)acetic acid (CAS 1022980-05-7)
- 1-Hydroxy-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid (CAS 103986-79-4)
- 1-Hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid (CAS 103986-80-7)
- 7-Hydroxy-4,4-dimethyl-3,4-dihydro-2h-1-benzopyran-2-one (CAS 111598-56-2)
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- Methyl 2-hydroxy-2,3-dihydro-1h-indene-2-carboxylate (CAS 1249067-50-2)
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Recommended Standards
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- Tert-Butyl 2-Ethylhexaneperoxoate (CAS 3006-82-4)
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