5-Chloro-3-phenethylthiophene-2-carboxylic acid CAS 74168-80-2
| CAS No. | 74168-80-2 |
| Molecular Formula | C13H11ClO2S |
| Molecular Weight | 266.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-Chloro-3-phenethylthiophene-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 5-Chloro-3-phenethylthiophene-2-carboxylic acid (CAS 74168-80-2), a certified reference material (molecular formula C13H11ClO2S, MW 266.74 g/mol) for analytical method development and quality control.
Based on its molecular formula C13H11ClO2S, 5-Chloro-3-phenethylthiophene-2-carboxylic acid contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 266.74 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C13H11ClO2S |
| Molecular Weight | 266.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
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- 4-Chloro-N-(2-(thiophen-2-yl)ethyl)picolinamide (CAS 1094306-31-6)
- 4-(2-Chloro-7-ethyl-7H-pyrrolo-[2,3-d]pyrimidin-4-yl)morpholine (CAS 1221688-88-5)
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- 4-Chloro-6-(1,3-dimethyl-1H-pyrazol-5-yl)-2-(1-methoxyethyl)pyrimidine (CAS 1707571-11-6)
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Recommended Standards
- 5-(4-Chlorophenyl)-4-ethylthiophene-2-carboxylic acid (CAS 861226-90-6)
- Diphenylmethanesulfonyl chloride (CAS 869676-42-6)
- 4'-Methyl-[1,1'-biphenyl]-3-sulfonylchloride (CAS 885950-93-6)
- 5-Amino-1-(2-chlorophenyl)-3-methyl-1H-pyrazole-4-carbothioamide (CAS 101309-61-9)
- Suc-Ala-Leu-Pro-Phe-pNA (L-1620.0050) (CAS 128802-78-8)
- 6-Chloro-5-cyclopropoxypicolinaldehyde (CAS 1243384-39-5)
- Ethyl 5-(2-Pyridyl)pyrazole-3-carboxylate (CAS 174139-65-2)
- 1-(Chloromethyl)-2-methylcyclopropane (CAS 89364-64-7)
- Hexahydro-1H-quinolizin-2(6H)-one (CAS 23581-42-2)
- (R)-tert-butyl 3-(hydroxymethyl)morpholine-4-carboxylate (CAS 215917-99-0)
- 5-(4-Methoxyphenyl)-4-(4-methylphenyl)-4H-1,2,4-triazole-3-thiol (CAS 328556-62-3)
- (1r)-1-(3-Bromothiophen-2-yl)ethan-1-ol (CAS 1344922-31-1)
- rel-tert-Butyl ((3R,5R)-5-(hydroxymethyl)pyrrolidin-3-yl)carbamate hydrochloride (CAS 1217680-19-7)
- Biotinyl-CBP501 Affinity Peptide trifluoroacetate salt (CAS 2022956-39-2)
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