1-(4-Fluorophenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one CAS 74169-57-6
| CAS No. | 74169-57-6 |
| Molecular Formula | C14H11FN2O2 |
| Molecular Weight | 258.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-(4-Fluorophenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one (CAS 74169-57-6) is a high-purity analytical reference standard with the molecular formula C14H11FN2O2 and a molecular weight of 258.25 g/mol.
The molecular framework of 1-(4-Fluorophenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one (C14H11FN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H11FN2O2 |
| Molecular Weight | 258.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- 2-Chloro-5-fluoro-3-(trifluoromethyl)benzyl alcohol (CAS 2056110-51-9)
- 4-Fluoro-3-(trifluoromethoxy)phenacyl bromide (CAS 1445973-45-4)
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- 4-Chloro-2,3'-bipyridine (CAS 31860-66-9)
- 4-Chloro-1-methyl-3-nitroquinolin-2(1H)-one (CAS 79966-13-5)
- Ethyl 2-(4-hydroxy-5-oxo-4-(trifluoromethyl)pyrrolidin-2-ylidene)acetate (CAS 1000933-95-8)
- 2-Phenylpyrazolo[1,5-a]pyridine-3-carboxylic acid (CAS 80537-07-1)
- D-Gln24-Tirzepatide (CAS CATO-CPTD788910)
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