5-Iodobenzofuran-2(3H)-one CAS 742079-78-3
| CAS No. | 742079-78-3 |
| Molecular Formula | C8H5IO2 |
| Molecular Weight | 260.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-Iodobenzofuran-2(3H)-one (CAS 742079-78-3), molecular formula C8H5IO2 and molecular weight 260.03 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system, 5-Iodobenzofuran-2(3H)-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 260.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 5-Iodobenzofuran-2(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5IO2 |
| Molecular Weight | 260.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | I-containing |
Related Iodobenzofuran Standards
- 2-Iodobenzofuran-6-ol (CAS 112768-48-6)
- 4-Iodobenzofuran-3(2H)-one (CAS 1199783-16-8)
- 7-Iodobenzofuran-3(2H)-one (CAS 20143-57-1)
- 6-iodobenzofuran-3-one (CAS 1199782-68-7)
- 6-iodobenzofuran (CAS 1158745-23-3)
- 6-Iodobenzofuran-3-carbaldehyde (CAS 1255099-10-5)
- (6-Iodobenzofuran-2-yl)methanol (CAS 1089682-09-6)
- (6-Iodobenzofuran-3-yl)methanol (CAS 1255099-73-0)
Recommended Standards
- 5-Iodobenzo[d]oxazol-2-amine (CAS 64037-13-4)
- 5-Iodoisobenzofuran-1(3H)-one (CAS 41284-92-8)
- 5-Iodobenzene-1,3-dicarbaldehyde (CAS 859238-51-0)
- 6-Bromo-4,7-difluoroisoquinolin-1(2H)-one (CAS 2857816-54-5)
- N-((1H-benzo[d]imidazol-2-yl)methyl)-2-chlorobenzamide (CAS 338410-53-0)
- Bromhexine Impurity 22 (CAS 114059-99-3)
- 5-Bromo-4-fluoro-2-hydroxybenzonitrile (CAS 1445967-94-1)
- Tranylcypromine Impurity 1 (CAS 14561-40-1)
- (Ethene-1,1,2,2-tetrayltetrakis(benzene-4,1-diyl))tetramethanaminetetrahydrochloride (CAS 2309406-51-5)
- 1-(4-(2-(2-(Diethylamino)-1-hydroxyethyl)-1H-pyrrol-1-yl)benzyl)-3-isopropylurea (CAS 866010-80-2)
- 1-(4-Bromophenyl)-1,3,8-triazaspiro[4.5]decan-4-one (CAS 61271-81-6)
- 5-chlorocinnolin-4-ol (CAS 1076-16-0)
- Methyl 2-(1H-pyrazole-3-carboxamido)thiophene-3-carboxylate (CAS 763107-52-4)
- C-Peptide (human) (CAS 33017-11-7)
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