3-(3-Chlorophenyl)-1-methylpyrrolidine-2,5-dione CAS 74208-84-7
| CAS No. | 74208-84-7 |
| Molecular Formula | C11H10ClNO2 |
| Molecular Weight | 223.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(3-Chlorophenyl)-1-methylpyrrolidine-2,5-dione (C11H10ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
3-(3-Chlorophenyl)-1-methylpyrrolidine-2,5-dione (CAS 74208-84-7) is a high-purity analytical reference standard with the molecular formula C11H10ClNO2 and a molecular weight of 223.66 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(3-Chlorophenyl)-1-methylpyrrolidine-2,5-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H10ClNO2 |
| Molecular Weight | 223.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorophenyl Standards
- 1-(5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl)-N-methylmethanamine (CAS 1017782-52-3)
- 2-(3-(3-Chlorophenyl)-1,2,4-oxadiazol-5-yl)ethanamine (CAS 1018613-23-4)
- (2-(4-CHLOROPHENYL)-5-METHYLOXAZOL-4-YL)METHANOL (CAS 109544-17-4)
- [2-(3-Chlorophenyl)-4-methyl-1,3-oxazol-5-yl]methanol (CAS 109544-34-5)
- 1-(3-(4-Chlorophenyl)isoxazol-5-yl)ethan-1-ol (CAS 109572-24-9)
- 4-(3-Chlorophenyl)piperidine-2,6-dione (CAS 113675-65-3)
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Recommended Standards
- 3-(2-Chlorophenyl)-5-ethoxy-1H-1,2,4-triazole (CAS 62036-05-9)
- 3-(3-Chlorophenyl)-5-ethoxy-1H-1,2,4-triazole (CAS 62036-04-8)
- 3-(2-Chlorophenyl)-2-cyano-2-methylpropanoic acid (CAS 606148-91-8)
- 3-(4-Chlorophenyl)-5-ethoxy-1H-1,2,4-triazole (CAS 62036-03-7)
- 3-Methyl-N-phenylbenzamide (CAS 23099-05-0)
- 2-Bromo-5-(3,3-difluoropropoxy)pyridine (CAS 1620691-31-7)
- N-hydroxy-2-pyrrolidin-1-yl-acetamidine (CAS 1017047-83-4)
- N7-(2-Hydroxyethyl-d4)adenine (CAS 1246818-44-9)
- 3-(4-Chlorophenyl)-1-(p-tolyl)-1H-pyrazol-5-amine (CAS 84637-30-9)
- 4-(2,4-dimethoxyphenyl)-6-methyl-isoxazolo[5,4-b]pyridin-3-amine (CAS 1226304-89-7)
- 2,4-Dimethoxybenzenesulfonyl chloride (CAS 63624-28-2)
- 2-(2-Bromoethoxy)propane (CAS 54149-16-5)
- (((2S,3S,4R)-3-hydroxy-4-(2-hydroxyphenoxy)tetrahydro-2H-pyran-2-yl)methyl)diphenylphosphine oxide (CAS 291273-51-3)
- Tirzepatide Impurity 44 (CAS CATO-C4X-324044)
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