1,8-Dihydroxy-2-methoxy-3-methylanthracene-9,10-dione CAS 74272-75-6

Purity 97%+In StockPharmaceutical Standards
CAS No.74272-75-6
Molecular FormulaC16H12O5
Molecular Weight284.26 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1,8-Dihydroxy-2-methoxy-3-methylanthracene-9,10-dione CAS 74272-75-6 chemical structure

Description

The occurrence of 1,8-Dihydroxy-2-methoxy-3-methylanthracene-9,10-dione is closely related to a flavonoid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1,8-Dihydroxy-2-methoxy-3-methylanthracene-9,10-dione (CAS 74272-75-6), molecular formula C16H12O5 and molecular weight 284.26 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1,8-Dihydroxy-2-methoxy-3-methylanthracene-9,10-dione (C16H12O5) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC16H12O5
Molecular Weight284.26 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1978

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