(2E)-3-(4-Ethoxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one CAS 74280-20-9
| CAS No. | 74280-20-9 |
| Molecular Formula | C18H18O3 |
| Molecular Weight | 282.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies (2E)-3-(4-Ethoxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one (CAS 74280-20-9), a certified reference material (molecular formula C18H18O3, MW 282.33 g/mol) for analytical method development and quality control.
The molecular framework of (2E)-3-(4-Ethoxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one (C18H18O3) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H18O3 |
| Molecular Weight | 282.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
Related E Standards
- (2E)-3-(2-Ethoxyphenyl)-1-(2-methoxyphenyl)prop-2-en-1-one (CAS 1175867-24-9)
- (2E)-3-(4-Ethoxyphenyl)-1-(2-methoxyphenyl)prop-2-en-1-one (CAS 1181788-49-7)
- (2E)-1-(4-Ethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one (CAS 158575-01-0)
- (2E)-1-(4-Ethoxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one (CAS 1801686-30-5)
- (2E)-1-(4-Ethoxyphenyl)-3-(3-methoxyphenyl)prop-2-en-1-one (CAS 6002-50-2)
- (2E)-3-(2-Ethoxyphenyl)-1-(3-methoxyphenyl)prop-2-en-1-one (CAS 358656-49-2)
- (2E)-3-(2-Ethoxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one (CAS 358656-32-3)
- (2E)-3-(4-Ethoxyphenyl)-1-(3-methoxyphenyl)prop-2-en-1-one (CAS 358656-50-5)
Recommended Standards
- (3-(1,3-Dioxolan-2-yl)phenyl)(2,3-dimethylphenyl)methanone (CAS 898779-30-1)
- (2E)-3-(3,4-Dimethoxyphenyl)-1-(4-methylphenyl)prop-2-en-1-one (CAS 72666-54-7)
- (3-(1,3-Dioxolan-2-yl)phenyl)(2,4-dimethylphenyl)methanone (CAS 898779-33-4)
- (3-(1,3-Dioxolan-2-yl)phenyl)(2,5-dimethylphenyl)methanone (CAS 898779-36-7)
- 1,5-Diamino-4-(1,3-benzothiazol-2-yl)-2,3-dihydro-1h-pyrrol-3-one (CAS 610278-85-8)
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