Imipenem intermediate: p-Nitrobenzyl Ester CAS 74288-40-7
| CAS No. | 74288-40-7 |
| Molecular Formula | C16H16N2O7 |
| Molecular Weight | 348.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Imipenem intermediate: p-Nitrobenzyl Ester (C16H16N2O7) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Imipenem intermediate: p-Nitrobenzyl Ester (CAS 74288-40-7), molecular formula C16H16N2O7 and molecular weight 348.31 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H16N2O7 |
| Molecular Weight | 348.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 2 |
Related Imipenem Standards
- Imipenem Impurity 111 (CAS CATO-C4X-1662111)
- Imipenem Impurity 112 (CAS CATO-C4X-1662112)
- Imipenem Impurity 113 (CAS CATO-C4X-1662113)
- Imipenem Impurity 114 (CAS CATO-C4X-1662114)
- Imipenem Impurity 127 (CAS CATO-C4X-1662127)
- Imipenem Impurity 129 (CAS CATO-C4X-1662129)
- Imipenem Impurity 105 (CAS CATO-C4X-1662105)
- Imipenem Impurity 131 (CAS CATO-C4X-1662131)
Recommended Standards
- 5-(((2,4-Dichlorobenzyl)thio)methyl)-4-isopropyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 344272-66-8)
- Justicidin E (CAS 27792-97-8)
- 4-Nitrobenzyl 6-(1-hydroxyethyl)-3,7-dioxo-1-azabicyclo[3.2.0]heptane-2-carboxylate (CAS 77449-43-5)
- Methyl 2-(1,3-dioxoisoindolin-2-yl)-3-hydroxyquinoline-6-carboxylate (CAS 2435612-51-2)
- n-(4-Acetylphenyl)-2-chlorobenzamide (CAS 84833-22-7)
- 1-(4,5-Dihydroisoxazol-3-yl)-2-phenylethan-1-amine (CAS 1258640-70-8)
- 1-(2-carboxyethyl)-3-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1245808-63-2)
- 2,5-Dioxo-4-pentylimidazolidine-4-carbaldehyde (CAS 5454-68-2)
- 5-Chloro-2,3-dimethoxypyridine hydrochloride (CAS 1704065-35-9)
- 1,4-Dimethyl-3-phenyl-1h-pyrazol-5-amine (CAS 30830-04-7)
- 6-Methylpiperidine-2-carboxylic acid (CAS 99571-58-1)
- decahydroquinoline-3-carboxylic acid hydrochloride (CAS 2031260-80-5)
- (4-Fluorophenyl)(5-hydroxybenzofuran-3-yl)methanone (CAS 312513-28-3)
- Insulin Degludec Impurity 28 (CAS CATO-C4X-215728)
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