2-Amino-3,5-dibromo-6-methylpyrazine CAS 74290-66-7
| CAS No. | 74290-66-7 |
| Molecular Formula | C5H5Br2N3 |
| Molecular Weight | 266.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 2-Amino-3,5-dibromo-6-methylpyrazine (CAS 74290-66-7), a certified reference material (molecular formula C5H5Br2N3, MW 266.92 g/mol) for analytical method development and quality control.
The molecular framework of 2-Amino-3,5-dibromo-6-methylpyrazine (C5H5Br2N3) is characterized by a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C5H5Br2N3 |
| Molecular Weight | 266.92 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 2-Amino-4,5-dibromophenol (CAS 1037298-16-0)
- 2-Amino-4,6-dibromophenol (CAS 10539-14-7)
- 2-Amino-3,5-dibromophenol (CAS 116632-17-8)
- 5-Amino-2,3-dibromophenol (CAS 116632-19-0)
- 4-Amino-3,5-dibromophenol (CAS 188721-64-4)
- 4-Amino-2,5-dibromophenol (CAS 872272-33-8)
- 5-amino-2,4-dibromophenol (CAS 367521-07-1)
- 6-Amino-5-iodo-1-methylpyrimidine-2,4(1H,3H)-dione (CAS 127829-66-7)
Recommended Standards
- 2,6-Dibromo-N-methylpyrimidin-4-amine (CAS 425425-29-2)
- 3,4-Diamino-2,5-dibromopyridine (CAS 221241-11-8)
- 2,6-Dibromo-4-methylpyridin-3-ol (CAS 2852767-48-5)
- 3,4-Dibromo-2-methoxypyridine (CAS 96245-99-7)
- 2-Bromo-1-(3-(4-chlorophenyl)-5-methylisoxazol-4-yl)ethan-1-one (CAS 1159981-10-8)
- 2-(PIperazin-1-ylmethyl)phenylboronic acid (CAS 1220636-65-6)
- 6-Bromo-5-methoxy-1,2-dimethyl-1H-indole-3-carbaldehyde (CAS 111083-32-0)
- 4-Bromo-3-fluoro-2-nitropyridine (CAS 1805578-63-5)
- Dodecyl 4,6-dibromothieno[3,4-b]thiophene-2-carboxylate (CAS 1098102-93-2)
- [1-(pyridin-2-yl)cyclopropyl]methanamine dihydrochloride (CAS 1228878-74-7)
- 2-(furan-3-yl)-1,3-thiazole-5-carboxylic acid (CAS 1333946-90-9)
- 5-(oxan-4-yl)piperidine-2,4-dione (CAS 1547092-68-1)
- 5-(Bromomethyl)-3-(1-methyl-1h-pyrazol-4-yl)-1,2-oxazole (CAS 1341608-81-8)
- Semaglutide Impurity 165 (CAS CATO-C4X-2226165)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com