2-Amino-5-bromo-6-methylpyrazine CAS 74290-69-0
| CAS No. | 74290-69-0 |
| Molecular Formula | C5H6BrN3 |
| Molecular Weight | 188.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 188.03 g/mol gives 2-Amino-5-bromo-6-methylpyrazine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Amino-5-bromo-6-methylpyrazine (CAS 74290-69-0), molecular formula C5H6BrN3 and molecular weight 188.03 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrile group, bromine substitution, 2-Amino-5-bromo-6-methylpyrazine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 188.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Amino-5-bromo-6-methylpyrazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H6BrN3 |
| Molecular Weight | 188.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 3-Amino-4-bromo-6-methylpyridazine (CAS 1260890-22-9)
- 2-Amino-5-bromo-4-methylpyrimidine (CAS 17321-93-6)
- 2-Amino-3-bromo-6-methylpyrazine (CAS 2166787-89-7)
- 4-Amino-5-bromo-6-methylpyrimidine 7752-48-9 C5H6BrN3 W8411 (CAS 7752-48-9)
- 3-Amino-2-bromophenol (CAS 100367-36-0)
- 3-Amino-4-bromophenol (CAS 100367-37-1)
- 3-Amino-5-bromophenol (CAS 100367-38-2)
- 2-Amino-3-bromophenol (CAS 116435-77-9)
Recommended Standards
- 2-Bromo-4-hydrazinylpyridine (CAS 923547-35-7)
- 2-(2-Vinylphenyl)-1,3,2-dioxaborinane (CAS 850567-61-2)
- 2-Bromo-6-hydrazinopyridine (CAS 26944-71-8)
- 2-(1-Phenylvinyl)-1,3,2-dioxaborinane (CAS 415727-02-5)
- 2-Amino-4-cyclopropyl-5-(methylsulfonyl)thiophene-3-carbonitrile (CAS 1707379-15-4)
- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(3,4-difluorophenyl)acetamide (CAS 303091-74-9)
- 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(4-fluorophenyl)acetamide (CAS 672950-14-0)
- Candesartan tert-Butyl Ester (CAS 1246820-49-4)
- (6-phenoxypyridin-3-yl)methanamine (CAS 620608-78-8)
- Benzoic acid, 4-(3-hydroxy-1-propen-1-yl)-, methyl ester (CAS 87808-23-9)
- n-Cyclopentyl-4,4-dimethylcyclohexan-1-amine (CAS 1339183-07-1)
- Goserelin EP Impurity E TFA Salt (CAS 147688-42-4(free base))
- (4-Ethoxy-3-methoxyphenyl)(5-(3-methoxyphenyl)-1H-1,2,4-triazol-3-yl)methanamine (CAS 1707376-78-0)
- Semaglutide Impurity 192 (CAS CATO-C4X-2226192)
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