2-Amino-3-(4-hydroxy-3,5-diiodophenyl)-2-methylpropanoic acid CAS 7434-77-7
| CAS No. | 7434-77-7 |
| Molecular Formula | C10H11I2NO3 |
| Molecular Weight | 447.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Amino-3-(4-hydroxy-3,5-diiodophenyl)-2-methylpropanoic acid.
2-Amino-3-(4-hydroxy-3,5-diiodophenyl)-2-methylpropanoic acid (CAS 7434-77-7), molecular formula C10H11I2NO3 and molecular weight 447.01 g/mol, is a CATO reference standard with documented purity and traceability.
2-Amino-3-(4-hydroxy-3,5-diiodophenyl)-2-methylpropanoic acid (C10H11I2NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Amino-3-(4-hydroxy-3,5-diiodophenyl)-2-methylpropanoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H11I2NO3 |
| Molecular Weight | 447.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
- 5-Amino-3-cyano-4-iodo-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]pyrazole (CAS 188539-59-5)
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- 33869-21-5 7-Amino-8-(2,4-dihydroxyphenyl)-2-(2-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)-2,10-dihydro-3H-phenoxazin-3-one--8-(2,4-dihydroxyphenyl)-7-hydroxy-2-(2-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)-2,10-dihydro-3H-phenoxazin-3-one (1/1) DTXSID70657601 (CAS 33869-21-5)
- (2S)-2-Amino-N1-(1-((S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidin-2-yl)-1,3-dioxobutan-2-yl)succinamide (CAS 82867-72-9)
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Recommended Standards
- (S)-Methyl 2-amino-3-(4-hydroxy-3,5-diiodophenyl)propanoate (CAS 76318-50-8)
- 4-[(4-tert-Butylphenyl)sulfanyl]-6-[(4-chlorobenzenesulfonyl)methyl]-2-methylpyrimidine (CAS 338960-58-0)
- 0615AD 1186311-08-9 C10H11I2NO3 tert-Butyl 3,5-diiodopyridin-4-yl carbonate (CAS 1186311-08-9)
- 4-hydroxy-3,5-diiodo-[1,1-biphenyl]-4-carbonitrile (CAS 340314-21-8)
- N-Benzyl-N-methylpiperidine-3-carboxamide (CAS 879619-70-2)
- N-Hydroxy-N,1-dimethylpyrrolidine-2-carboxamide (CAS 121531-14-4)
- 2,2,3,3,3-Pentafluoro-1-mesitylpropan-1-one (CAS 1443346-16-4)
- 2-Amino-2-ethylbutanenitrile hydrochloride (CAS 859081-90-6)
- 3-nitro-7,8-dihydro-5H-quinolin-6-one (CAS 881668-73-1)
- (S)-2-Aminopropanoic acid hydrochloride (CAS 6003-05-0)
- 1-(2-Hydrazinylthiazol-5-yl)-N,N-dimethylmethanamine (CAS 1501697-72-8)
- 5,6-Dimethyl-4-nitro-1-octyl-1H-benzo[d]imidazole (CAS 338954-97-5)
- Boc-trans-DL-β-Pro-4-(3-cyanophenyl)-OH (CAS 959580-33-7)
- Brain Injury Derived Neurotrophic Peptide (H-3914.0001) (CAS 148330-12-5)
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