(2Z)-2-(chloroacetyl)-3-(diethylamino)-3-(4-fluorophenyl)acrylonitrile CAS 743440-17-7

Purity 97%+In StockPharmaceutical Standards
CAS No.743440-17-7
Molecular FormulaC15H16ClFN2O
Molecular Weight294.75 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2Z)-2-(chloroacetyl)-3-(diethylamino)-3-(4-fluorophenyl)acrylonitrile CAS 743440-17-7 chemical structure

Description

CATO supplies (2Z)-2-(chloroacetyl)-3-(diethylamino)-3-(4-fluorophenyl)acrylonitrile (CAS 743440-17-7), a certified reference material (molecular formula C15H16ClFN2O, MW 294.75 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, (2Z)-2-(chloroacetyl)-3-(diethylamino)-3-(4-fluorophenyl)acrylonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 294.75 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (2Z)-2-(chloroacetyl)-3-(diethylamino)-3-(4-fluorophenyl)acrylonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC15H16ClFN2O
Molecular Weight294.75 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1986
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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