2-Chloro-5-[cyclohexyl(methyl)sulfamoyl]benzoic acid CAS 743451-72-1
| CAS No. | 743451-72-1 |
| Molecular Formula | C14H18ClNO4S |
| Molecular Weight | 331.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-Chloro-5-[cyclohexyl(methyl)sulfamoyl]benzoic acid (CAS 743451-72-1), molecular formula C14H18ClNO4S and molecular weight 331.82 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 2-Chloro-5-[cyclohexyl(methyl)sulfamoyl]benzoic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 331.82 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H18ClNO4S |
| Molecular Weight | 331.82 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 3-[(2-Chloro-5-methylphenoxy)methyl]-4-phenyl-4,5-dihydro-1H-1,2,4-triazole-5-thione (CAS 1024387-54-9)
- 1-(2-Chloro-5-methyl-4-(methylsulfonyl)phenyl)piperidine-4-carboxylic acid (CAS 942474-74-0)
- 1-[(2-Chloro-4-methylsulfonyl)phenyl]piperidine-3-carbohydrazide (CAS 951625-09-5)
- 1-[2-Chloro-5-methyl-4-(methylsulfonyl)phenyl]-piperidine-3-carboxylic acid (CAS 942474-28-4)
- 2-Chloro-5-[(3,5-dimethylpiperidin-1-yl)sulfonyl]benzoic acid (CAS 24358-29-0)
- 3-[(4-Chloro-2-methylphenoxy)methyl]-4-phenyl-4,5-dihydro-1H-1,2,4-triazole-5-thione (CAS 21358-23-6)
- 3-Chloro-N-(2-methoxyphenyl)-6-methylbenzo[b]thiophene-2-carboxamide (CAS 312938-74-2)
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Recommended Standards
- 3-(4-Chlorobenzyl)-4-hydroxy-1-(thiophen-2-ylmethyl)pyridin-2(1H)-one (CAS 303994-53-8)
- 2-(5-((2-Chlorobenzyl)thio)-4-ethyl-4H-1,2,4-triazol-3-yl)pyrazine (CAS 618427-46-6)
- 1-Benzyl-3-[(4-chlorophenyl)sulfanyl]pyrrolidine-2,5-dione (CAS 321433-49-2)
- 4-(((4-Chlorophenyl)sulfonamido)methyl)cyclohexane-1-carboxylic acid (CAS 317375-82-9)
- 1-Isopropyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one (CAS 923283-88-9)
- 4-Bromo-5-methyl-1H-pyrrolo[2,3-c]pyridine (CAS 1257294-45-3)
- 4-(3,5-Dimethoxybenzamido)benzoic acid (CAS 54057-47-5)
- 4-Bromo-2-(2,2,2-trifluoroethyl)pyridazin-3(2h)-one (CAS 2167219-71-6)
- Candesartan Cilexetil EP Impurity F (CAS 914613-36-8)
- {2-[4-(1H-1,2,4-triazol-1-ylmethyl)phenyl]phenyl}methanamine (CAS 926229-69-8)
- 3-[(3-Phenylpropoxy)methyl]pyrrolidine (CAS 946682-20-8)
- 1-(2-(2,4-Dimethylphenoxy)ethyl)-1H-pyrazole (CAS 956574-26-8)
- 3-[(2-Ethoxy-3,4-dioxocyclobutyl)amino]-2-hydroxy-N,N-dimethylbenzamide 919349-40-9 (CAS 919349-40-9)
- Semaglutide impurity 98 (CAS CATO-C4X-222698)
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