4-Bromo-2,6-dimethylbenzoyl chloride CAS 74346-20-6
| CAS No. | 74346-20-6 |
| Molecular Formula | C9H8BrClO |
| Molecular Weight | 247.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 247.52 g/mol gives 4-Bromo-2,6-dimethylbenzoyl chloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Bromo-2,6-dimethylbenzoyl chloride (CAS 74346-20-6), molecular formula C9H8BrClO and molecular weight 247.52 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Bromo-2,6-dimethylbenzoyl chloride (C9H8BrClO) is characterized by a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Bromo-2,6-dimethylbenzoyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8BrClO |
| Molecular Weight | 247.52 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl/Br-containing |
Related Bromo Standards
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- Benzo[j]phenanthridin-6(5H)-one (CAS 2413-02-7)
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- 2-(2-Cyanophenoxy)ethane-1-sulfonyl chloride (CAS 1342655-60-0)
- Methyl 2-(4-(3-bromopropoxy)phenoxy)acetate 910032-57-4 (CAS 910032-57-4)
- 4-Bromo-5-cyclopropoxypyridin-2-amine (CAS 1243452-50-7)
- N-(3-Fluoro-2-(trifluoromethyl)-phenyl)piperidin-1-amine (CAS 1713163-59-7)
- Des-Lys16-Tirzepatide (CAS CATO-CPTD788957)
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