Tert-butyl 4-(3-fluoro-2-formylphenyl)piperazine-1-carboxylate CAS 744219-30-5
| CAS No. | 744219-30-5 |
| Molecular Formula | C16H21FN2O3 |
| Molecular Weight | 308.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies Tert-butyl 4-(3-fluoro-2-formylphenyl)piperazine-1-carboxylate (CAS 744219-30-5), a certified reference material (molecular formula C16H21FN2O3, MW 308.35 g/mol) for analytical method development and quality control.
The molecular framework of Tert-butyl 4-(3-fluoro-2-formylphenyl)piperazine-1-carboxylate (C16H21FN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Tert-butyl 4-(3-fluoro-2-formylphenyl)piperazine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H21FN2O3 |
| Molecular Weight | 308.35 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- Tert-butyl 4-(2-fluorobenzoyl)piperazine-1-carboxylate (CAS 828298-39-1)
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- N-cyclohexyl-2,3-dioxoindoline-5-sulfonamide (CAS 451460-02-9)
- 501126-37-0 tert-Butyl 4-(2-fluoro-4-formylphenyl)piperazine-1-carboxylate DTXSID00609794 (CAS 501126-37-0)
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- 8-(tert-Bbutyl)-3,4-dihydroisoquinolin-1(2H)-one (CAS 1447-47-8)
- H-Pyr-His-Trp-OH (CAS CATO-CPTD788542)
- 1-Cyclopentyl-3-methyl-4-nitro-1H-pyrazole (CAS 1171752-78-5)
- Semaglutide impurity 23 (CAS CATO-C4X-222623)
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