tert-Butyl4-(3-iodo-1H-indazol-4-yl)piperazine-1-carboxylate CAS 744219-32-7
| CAS No. | 744219-32-7 |
| Molecular Formula | C16H21IN4O2 |
| Molecular Weight | 428.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
tert-Butyl4-(3-iodo-1H-indazol-4-yl)piperazine-1-carboxylate (C16H21IN4O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
tert-Butyl4-(3-iodo-1H-indazol-4-yl)piperazine-1-carboxylate (CAS 744219-32-7) is a high-purity analytical reference standard with the molecular formula C16H21IN4O2 and a molecular weight of 428.27 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), tert-Butyl4-(3-iodo-1H-indazol-4-yl)piperazine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H21IN4O2 |
| Molecular Weight | 428.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 4 |
Recommended Standards
- 1-(Tert-butyl) 2-methyl (2S,4S)-4-(3-bromo-4-formylphenoxy)pyrrolidine-1,2-dicarboxylate (CAS 2442510-71-4)
- tert-Butyl4-(3-iodo-1H-indazol-6-yl)piperazine-1-carboxylate (CAS 744219-44-1)
- (2,4-Dichlorophenyl)(1-methyl-5-(5-(phenoxymethyl)-1,3,4-oxadiazol-2-yl)-1H-pyrrol-3-yl)methanone (CAS 338418-65-8)
- 8-(Tributylstannyl)isoquinoline (CAS 1245816-24-3)
- ethyl 2-(3-chloropyridin-4-yl)acetate (CAS 1236306-08-3)
- 8-Bromo-6-nitroquinazolin-4-ol (CAS 1133000-12-0)
- 2,5-Dimethyl-4-phenylthiazole (CAS 19968-59-3)
- 5-Iodo-1H-pyrrolo[3,2-b]pyridine (CAS 1261811-86-2)
- Nitroxynil (CAS 1689-89-0)
- 2-Amino-5-nitrobenzaldehyde (CAS 56008-61-8)
- 1-Formylpiperazine (CAS 7755-92-2)
- 6-Methoxy-1-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 35975-68-9)
- 4-(Difluoromethoxy)-5-fluoro-2-(1h-1,2,4-triazol-1-yl)aniline (CAS 1411217-07-6)
- Tirzepatide Impurity 46 (CAS CATO-C4X-324046)
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