4-(1,3-Dioxoisoindolin-2-yl)butyl 2-(methylthio)nicotinate CAS 744240-29-7
| CAS No. | 744240-29-7 |
| Molecular Formula | C19H18N2O4S |
| Molecular Weight | 370.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(1,3-Dioxoisoindolin-2-yl)butyl 2-(methylthio)nicotinate.
CATO supplies 4-(1,3-Dioxoisoindolin-2-yl)butyl 2-(methylthio)nicotinate (CAS 744240-29-7), a certified reference material (molecular formula C19H18N2O4S, MW 370.42 g/mol) for analytical method development and quality control.
The molecular framework of 4-(1,3-Dioxoisoindolin-2-yl)butyl 2-(methylthio)nicotinate (C19H18N2O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H18N2O4S |
| Molecular Weight | 370.42 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Dioxoisoindolin Standards
- [(2R)-2-(1,3-dioxoisoindolin-2-yl)propyl] 4-methylbenzenesulfonate (CAS 101660-96-2)
- 1,3-Dioxoisoindolin-2-yl 2-(2,4-dichlorophenoxy)acetate (CAS 709639-63-4)
- 4-(1,3-Dioxoisoindolin-2-yl)-N-((hydroxymethyl)carbamoyl)benzenesulfonamide (CAS 16508-61-5)
- 4-(1,3-Dioxoisoindolin-2-yl)-N-(4-methylthiazol-2-yl)benzamide (CAS 378213-74-2)
- 2-(1,3-Dioxoisoindolin-2-yl)-N-(4-methoxyphenyl)ethanesulfonamide (CAS 872787-58-1)
- 1,3-Dioxoisoindolin-2-yl (1s,3s)-3-((tert-butoxycarbonyl)amino)cyclobutane-1-carboxylate (CAS 2248201-94-5)
- Ethyl 4-((1,3-dioxoisoindolin-2-yl)oxy)-2-(methylthio)pyrimidine-5-carboxylate (CAS 15400-45-0)
- N-(11-(1,3-Dioxoisoindolin-2-yl)undecyl)acetamide (CAS 90903-96-1)
Recommended Standards
- 3-((4-(tert-Butoxycarbonyl)piperazin-1-yl)sulfonyl)benzoicacid (CAS 874838-79-6)
- 4-Amino-5-benzoyl-2-(naphthalen-2-yloxy)thiophene-3-carbonitrile (CAS 478248-34-9)
- 2-{[6-(4-Methylphenyl)imidazo[2,1-b][1,3]thiazol-5-yl]methylene}-1H-indene-1,3(2H)-dione (CAS 861213-01-6)
- Boc-Met-ONp (CAS 2488-18-8)
- (S)-1-Benzyl 2-methyl 4-propyl-1H-pyrrole-1,2(2H,5H)-dicarboxylate (CAS 1798902-94-9)
- Tert-butyl 5-bromo-3-isopropyl-1H-pyrrolo[3,2-b]pyridine-1-carboxylate (CAS 2351275-18-6)
- 2-Methyl-2-(4-methylpiperidin-1-yl)propan-1-amine 3580AF 933724-18-6 C10H22N2 (CAS 933724-18-6)
- 2,4-Dibromo-3-chloro-6-ethoxyaniline (CAS 1706444-61-2)
- 1-(4-phenyl-1H-imidazol-2-yl)cyclopentan-1-amine dihydrochloride (CAS 1303890-54-1)
- (2-(3-Methoxyphenyl)benzo[d]oxazol-5-yl)methanol (CAS 1483064-47-6)
- 4-Chloro-N'-methyl-N'-(3-phenyl-6-(trifluoromethyl)-1,2,4-triazin-5-yl)benzohydrazide (CAS 672950-95-7)
- 3-Ethylazetidine hydrochloride (CAS 1798795-28-4)
- Sodium 4-(3-(pyridin-2-yl)-6-(4-sulfophenyl)-1,2,4-triazin-5-yl)benzenesulfonate xhydrate (CAS 1266615-85-3)
- Semaglutide impurity 45 (CAS CATO-C4X-222645)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com