1-(3,5-Dichlorobenzoyl)pyrrolidine-2-carboxylic acid CAS 744253-60-9
| CAS No. | 744253-60-9 |
| Molecular Formula | C12H11Cl2NO3 |
| Molecular Weight | 288.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-(3,5-Dichlorobenzoyl)pyrrolidine-2-carboxylic acid (CAS 744253-60-9), a certified reference material (molecular formula C12H11Cl2NO3, MW 288.13 g/mol) for analytical method development and quality control.
1-(3,5-Dichlorobenzoyl)pyrrolidine-2-carboxylic acid (C12H11Cl2NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H11Cl2NO3 |
| Molecular Weight | 288.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Dichlorobenzoyl Standards
- 1-(2,5-Dichlorobenzoyl)pyrrolidine-2-carboxylic acid (CAS 1101837-02-8)
- 1-(3,4-dichlorobenzoyl)pyrrolidine-2-carboxylic acid (CAS 62559-51-7)
- 5-(3,4-Dichlorobenzoyl)-N-methyl-1,3-thiazol-2-amine (CAS 339022-12-7)
- 4-(2,4-Dichlorobenzoyl)-1H-pyrrole-2-carboxylic acid (CAS 886361-05-3)
- 5-(2,5-Dichlorobenzoyl)-2,3-dihydro-1-benzofuran (CAS 1096942-33-4)
- 4-(2,3-Dichlorobenzoyl)-1H-pyrrole-2-carboxamide (CAS 338753-53-0)
- 4-(2,4-Dichlorobenzoyl)-1H-pyrrole-2-carboxamide (CAS 339023-64-2)
- 1187171-45-4 2-(3,4-Dichlorobenzoyl)-6-methoxypyridine MFCD13152888 (CAS 1187171-45-4)
Recommended Standards
- 1-(3,4-Dichlorobenzyl)-5-oxo-3-pyrrolidinecarboxylic acid (CAS 919016-51-6)
- 1-(3,5-Dichlorophenyl)-3-(methoxymethyl)pyrrolidine-2,5-dione (CAS 81949-88-4)
- 1-(3-Fluorophenyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 2223038-04-6)
- 1-(2-((4,6-Dichloro-2-methylpyrimidin-5-yl)amino)-4,5-dihydro-1H-imidazol-1-yl)ethan-1-one (CAS 75438-54-9)
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